Clinical Trials Browser

Phase 2 × INDUSTRY × Osteosarcoma × Clear all

Osteosarcoma

NCT05199584 2026-03-05

A Study Evaluating the Safety and Efficacy of ENV-101 (Taladegib) in Patients With Advanced Solid Tumors Harboring PTCH1 Loss of Function Mutations

CNSDermatologicEndocrineHead & NeckOther solid neoplasmSarcomaThoracic

Uveal Melanoma, Glioma, Adenoma, Islet Cell, Laryngeal Diseases, Medulloblastoma, Melanoma, Mesothelioma, Neuroblastoma, Pituitary Diseases, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Osteosarcoma

NCT04974008 2025-01-22

OST-164-01

Phase 2 Active not recruiting

39 enrolled

Sarcoma

Bone Neoplasms, Osteosarcoma

NCT05830123 2024-08-23

ARTEMIS-002: HS-20093 in Patients With Relapsed or Refractory Osteosarcoma and Other Sarcomas

Phase 2 Recruiting

170 enrolled

Sarcoma

Sarcoma, Osteosarcoma

NCT04154189 2024-07-22

A Study to Compare the Efficacy and Safety of Ifosfamide and Etoposide With or Without Lenvatinib in Children, Adolescents and Young Adults With Relapsed and Refractory Osteosarcoma

Phase 2 Completed

81 enrolled 22 charts

Sarcoma

Recurrence, Osteosarcoma

NCT01759303 2021-04-13

Study of Pazopanib in the Treatment of Osteosarcoma Metastatic to the Lung

Phase 2 Terminated

12 enrolled

Sarcoma

Osteosarcoma

NCT01650090 2019-08-07

Phase 2 Study of Inhaled Lipid Cisplatin in Pulmonary Recurrent Osteosarcoma

Phase 2 Completed

28 enrolled

Sarcoma

Osteosarcoma

NCT00617890 2018-08-23

A Study to Determine the Activity of Robatumumab (SCH 717454) in Participants With Relapsed Osteosarcoma or Ewing's Sarcoma (MK-7454-002/P04720)

Phase 2 Terminated

219 enrolled 13 charts

Sarcoma

Sarcoma, Ewing, Osteosarcoma, Neuroectodermal Tumors, Primitive, Peripheral

NCT00154388 2016-11-18

Phase II Study of Imatinib Mesylate in Patients With Life Threatening Malignant Rare Diseases

Phase 2 Completed

185 enrolled

BreastDermatologicGenitourinaryGynecologicLymphoidMyeloidOther hematologic neoplasmOther solid neoplasmPlasma cellSarcomaThoracic

Malignant mesenchymal tumor, Adenocarcinoma, Brenner Tumor, Carcinoma, Renal Cell, Chondrosarcoma, Chordoma, Carcinoma, Adenoid Cystic, Fibroma, Hemangiopericytoma, Hemangiosarcoma, Leiomyosarcoma, Leukemia, Mast-Cell, Liposarcoma, Mastocytosis, Melanoma, Mesothelioma, Multiple Myeloma, Pleural Neoplasms, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Thymoma, Hypereosinophilic Syndrome, Sarcoma, Endometrial Stromal, Dermatofibrosarcoma, Rhabdomyosarcoma, Embryonal, Seminoma, Carcinoma, Ductal, Breast, Neurofibrosarcoma, Primary Myelofibrosis, Small Cell Lung Carcinoma

NCT00093080 2015-02-13

Study of AP23573/MK-8669 (Ridaforolimus), A Mammalian Target of Rapamycin (mTOR) Inhibitor, in Participants With Advanced Sarcoma (MK-8669-018 AM1)(COMPLETED)

Phase 2 Completed

216 enrolled

Sarcoma

Leiomyosarcoma, Liposarcoma, Neoplasm Metastasis, Sarcoma, Osteosarcoma

NCT00503295 2014-10-02

Safety and Efficacy Study of REOLYSIN® in the Treatment of Bone and Soft Tissue Sarcomas Metastatic to the Lung

Phase 2 Completed

53 enrolled

Sarcoma

Fibrosarcoma, Leiomyosarcoma, Sarcoma, Osteosarcoma, Sarcoma, Synovial, Histiocytoma, Malignant Fibrous

NCT01002092 2014-09-03

A Study of Endostar Combined With Chemotherapy for Treatment of Osteosarcoma

Phase 2 Unknown

160 enrolled

Sarcoma

Osteosarcoma

NCT00523419 2011-06-28

Chemotherapy for Patients With Osteosarcoma

Phase 2 Completed

32 enrolled 16 charts

Sarcoma

Osteosarcoma

NCT00572130 2011-06-10

Phase II Study of Intravenous Rexin-G in Osteosarcoma

Phase 2 Completed

22 enrolled

Sarcoma

Osteosarcoma

NCT00520936 2011-02-25

A Study of Pemetrexed in Children With Recurrent Cancer

Phase 2 Completed

72 enrolled 17 charts

CNSSarcoma

Ependymoma, Medulloblastoma, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma

Clinical Trials

CabOSTar

A Study Evaluating the Safety and Efficacy of ENV-101 (Taladegib) in Patients With Advanced Solid Tumors Harboring PTCH1 Loss of Function Mutations

OST-164-01

ARTEMIS-002: HS-20093 in Patients With Relapsed or Refractory Osteosarcoma and Other Sarcomas

A Study to Compare the Efficacy and Safety of Ifosfamide and Etoposide With or Without Lenvatinib in Children, Adolescents and Young Adults With Relapsed and Refractory Osteosarcoma

Study of Pazopanib in the Treatment of Osteosarcoma Metastatic to the Lung

Phase 2 Study of Inhaled Lipid Cisplatin in Pulmonary Recurrent Osteosarcoma

A Study to Determine the Activity of Robatumumab (SCH 717454) in Participants With Relapsed Osteosarcoma or Ewing's Sarcoma (MK-7454-002/P04720)

Phase II Study of Imatinib Mesylate in Patients With Life Threatening Malignant Rare Diseases

Study of AP23573/MK-8669 (Ridaforolimus), A Mammalian Target of Rapamycin (mTOR) Inhibitor, in Participants With Advanced Sarcoma (MK-8669-018 AM1)(COMPLETED)

Safety and Efficacy Study of REOLYSIN® in the Treatment of Bone and Soft Tissue Sarcomas Metastatic to the Lung

A Study of Endostar Combined With Chemotherapy for Treatment of Osteosarcoma

Chemotherapy for Patients With Osteosarcoma

Phase II Study of Intravenous Rexin-G in Osteosarcoma

A Study of Pemetrexed in Children With Recurrent Cancer