Announcements Trials
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Phase

Phase NA 1Phase EARLY_PHASE1 1Phase 3 1

Status

Withdrawn 1Suspended 1Completed 1Active not recruiting 1

Sponsor Class

OTHER 3NIH 1

Study Type

Interventional 3Observational 1

Sponsor

Cancer Type

Gastrointestinal 2CNS 1

Conditions

Carcinoma, Non-Small-Cell Lung 543Squamous Cell Carcinoma of Head and Neck 280Head and Neck Neoplasms 257Lung Neoplasms 240Uterine Cervical Neoplasms 180Stomach Neoplasms 172Esophageal Neoplasms 161Nasopharyngeal Carcinoma 127Urinary Bladder Neoplasms 117Neoplasms 115Esophageal Squamous Cell Carcinoma 115Small Cell Lung Carcinoma 105Ovarian Neoplasms 92Breast Neoplasms 92Neoplasm Metastasis 89Cholangiocarcinoma 76Carcinoma, Squamous Cell 76Pancreatic Neoplasms 72Biliary Tract Neoplasms 71Oropharyngeal Neoplasms 57Mesothelioma, Malignant 57Carcinoma 55Adenocarcinoma Of Esophagus 52Recurrence 48Parkinson Disease 4, Autosomal Dominant Lewy Body 47Carcinoma, Ovarian Epithelial 46Nasopharyngeal Neoplasms 41Lymphoma 41Adenocarcinoma of Lung 41Gallbladder Neoplasms 39

Interventions

sodium thiosulfate 4Cisplatin 4Methotrexate 2Chemotherapy, Adjuvant 2Acetylcysteine 2tempol 1ebselen 1Vorinostat 1Vincristine 1Thioctic Acid 1Surveys and Questionnaires 1Sodium Chloride 1Restraint, Physical 1Radiotherapy, Intensity-Modulated 1Radiotherapy, Conformal 1Radiotherapy 1Radiosurgery 1Pantoprazole 1Mental Status and Dementia Tests 1Magnetic Resonance Spectroscopy 1Hydroxymethylglutaryl-CoA Reductase Inhibitors 1Hyaluronic Acid 1Hearing Tests 1Genetic Association Studies 1Drug Therapy 1Dexamethasone 1Cyclophosphamide 1Chemoradiotherapy 1Carboplatin 1Audiometry 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Ototoxicity × Cisplatin × Clear all
NCT05756660 2025-10-20

Sodium Thiosulfate Otoprotection During Salvage Cisplatin Therapy

Children's Hospital Medical Center, Cincinnati

Phase EARLY_PHASE1 Suspended
33 enrolled
Gastrointestinal

Ototoxicity, Neoplasms, Germ Cell and Embryonal, Hepatoblastoma

NCT00652132 2018-05-29

SIOPEL6

University of Birmingham

Phase 3 Completed
116 enrolled 1 FDA
Gastrointestinal

Ototoxicity, Liver Neoplasms, Hepatoblastoma

NCT02382068 2017-11-09

Dexamethasone in Preventing Hearing Loss in Patients Receiving Cisplatin

Ohio State University Comprehensive Cancer Center

Phase NA Withdrawn

Ototoxicity, Neoplasms

NCT00683319 2013-09-20

Observing Young Patients With Ependymoma Undergoing Standard Combination Chemotherapy

National Cancer Institute (NCI)

Active not recruiting
50 enrolled
CNS

Ototoxicity, Central Nervous System Neoplasms

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