Announcements Trials
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Phase

Phase NA 1Phase EARLY_PHASE1 1Phase 3 1

Status

Withdrawn 1Suspended 1Completed 1

Sponsor Class

OTHER 3

Study Type

Interventional 3Observational 1

Sponsor

Cancer Type

Gastrointestinal 2

Conditions

Carcinoma, Non-Small-Cell Lung 531Squamous Cell Carcinoma of Head and Neck 273Head and Neck Neoplasms 252Lung Neoplasms 238Uterine Cervical Neoplasms 176Stomach Neoplasms 168Esophageal Neoplasms 160Nasopharyngeal Carcinoma 123Urinary Bladder Neoplasms 116Esophageal Squamous Cell Carcinoma 114Neoplasms 113Small Cell Lung Carcinoma 103Breast Neoplasms 92Ovarian Neoplasms 89Neoplasm Metastasis 89Carcinoma, Squamous Cell 76Cholangiocarcinoma 75Pancreatic Neoplasms 71Biliary Tract Neoplasms 69Mesothelioma, Malignant 57Oropharyngeal Neoplasms 56Carcinoma 55Adenocarcinoma Of Esophagus 52Recurrence 47Parkinson Disease 4, Autosomal Dominant Lewy Body 47Carcinoma, Ovarian Epithelial 45Nasopharyngeal Neoplasms 41Lymphoma 41Adenocarcinoma of Lung 41Gallbladder Neoplasms 38

Interventions

sodium thiosulfate 4Cisplatin 3Acetylcysteine 2tempol 1ebselen 1Vorinostat 1Thioctic Acid 1Sodium Chloride 1Restraint, Physical 1Radiotherapy, Intensity-Modulated 1Radiotherapy, Conformal 1Pantoprazole 1Methotrexate 1Hydroxymethylglutaryl-CoA Reductase Inhibitors 1Hyaluronic Acid 1Hearing Tests 1Dexamethasone 1Chemotherapy, Adjuvant 1Audiometry 1Atorvastatin 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Interventional × Ototoxicity × Cisplatin × Clear all
NCT05756660 2025-10-20

Sodium Thiosulfate Otoprotection During Salvage Cisplatin Therapy

Children's Hospital Medical Center, Cincinnati

Phase EARLY_PHASE1 Suspended
33 enrolled
Gastrointestinal

Ototoxicity, Neoplasms, Germ Cell and Embryonal, Hepatoblastoma

NCT00652132 2018-05-29

SIOPEL6

University of Birmingham

Phase 3 Completed
116 enrolled 1 FDA
Gastrointestinal

Ototoxicity, Liver Neoplasms, Hepatoblastoma

NCT02382068 2017-11-09

Dexamethasone in Preventing Hearing Loss in Patients Receiving Cisplatin

Ohio State University Comprehensive Cancer Center

Phase NA Withdrawn

Ototoxicity, Neoplasms

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