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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Conditions

Non-Muscle Invasive Bladder Neoplasms 2Head and Neck Neoplasms 2Voice Disorders 1Urinary Bladder Neoplasms 1Thyroid Neoplasms 1Stomatitis 1Squamous Cell Carcinoma of Head and Neck 1Pleural Diseases 1Papilloma 1Ototoxicity 1Mesothelioma 1Laryngeal Neoplasms 1Hearing Loss 1Goiter 1Esophageal Neoplasms 1Deglutition Disorders 1Cystitis, Interstitial 1Arthralgia 1

Interventions

sodium thiosulfate 4Cisplatin 4Methotrexate 2Chemotherapy, Adjuvant 2Acetylcysteine 2tempol 1ebselen 1Vorinostat 1Vincristine 1Thioctic Acid 1Surveys and Questionnaires 1Sodium Chloride 1Restraint, Physical 1Radiotherapy, Intensity-Modulated 1Radiotherapy, Conformal 1Radiotherapy 1Radiosurgery 1Pantoprazole 1Mental Status and Dementia Tests 1Magnetic Resonance Spectroscopy 1Hydroxymethylglutaryl-CoA Reductase Inhibitors 1Hyaluronic Acid 1Hearing Tests 1Genetic Association Studies 1Drug Therapy 1Dexamethasone 1Cyclophosphamide 1Chemoradiotherapy 1Carboplatin 1Audiometry 1

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
Ototoxicity × Hyaluronic Acid × Clear all
NCT04262336 2023-07-06

Study to Evaluate Safety and Efficacy of DB-020 to Protect Hearing in Patients Receiving Cisplatin for Cancer Treatment

Decibel Therapeutics

Phase 1 Completed
22 enrolled

Ototoxicity, Hearing Loss

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