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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Conditions

Breast Neoplasms 33Colorectal Neoplasms 12Neoplasms 11Pain, Postoperative 10Lung Neoplasms 9Brain Neoplasms 8Stomach Neoplasms 7Prostatic Neoplasms 7Pancreatic Neoplasms 7Carcinoma, Non-Small-Cell Lung 7Melanoma 6Leukemia, Myeloid, Acute 5Ovarian Neoplasms 4Myoma 4Lymphoma, Non-Hodgkin 4Leiomyoma 4Hemorrhage 4Head and Neck Neoplasms 4Glioblastoma 4Colonic Neoplasms 4Agnosia 4Skin Neoplasms 3Recurrence 3Rectal Neoplasms 3Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Neurotoxicity Syndromes 3Neoplasm Metastasis 3Nasopharyngeal Carcinoma 3Myelodysplastic Syndromes 3Multiple Endocrine Neoplasia Type 1 3

Interventions

sodium thiosulfate 4Cisplatin 4Methotrexate 2Chemotherapy, Adjuvant 2Acetylcysteine 2tempol 1ebselen 1Vorinostat 1Vincristine 1Thioctic Acid 1Surveys and Questionnaires 1Sodium Chloride 1Restraint, Physical 1Radiotherapy, Intensity-Modulated 1Radiotherapy, Conformal 1Radiotherapy 1Radiosurgery 1Pantoprazole 1Mental Status and Dementia Tests 1Magnetic Resonance Spectroscopy 1Hydroxymethylglutaryl-CoA Reductase Inhibitors 1Hyaluronic Acid 1Hearing Tests 1Genetic Association Studies 1Drug Therapy 1Dexamethasone 1Cyclophosphamide 1Chemoradiotherapy 1Carboplatin 1Audiometry 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Ototoxicity × Sodium Chloride × Clear all
NCT04262336 2023-07-06

Study to Evaluate Safety and Efficacy of DB-020 to Protect Hearing in Patients Receiving Cisplatin for Cancer Treatment

Decibel Therapeutics

Phase 1 Completed
22 enrolled

Ototoxicity, Hearing Loss

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