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Phase

Phase EARLY_PHASE1 1Phase 3 1

Status

Suspended 1Completed 1

Sponsor Class

OTHER 2NETWORK 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Gastrointestinal 2

Conditions

Mesothelioma, Malignant 5Hepatoblastoma 3Drug-Related Side Effects and Adverse Reactions 3Central Nervous System Neoplasms 3Ototoxicity 2Oligodendroglioma 2Neoplasms, Germ Cell and Embryonal 2Medulloblastoma 2Glioma 2Gastrointestinal Neoplasms 2Astrocytoma 2Thrombocytopenia 1Testicular Neoplasms 1Stomach Neoplasms 1Seminoma 1Sarcoma 1Rhabdomyosarcoma 1Rectal Neoplasms 1Peritoneal Neoplasms 1Pelvic Neoplasms 1Ovarian Neoplasms 1Oropharyngeal Neoplasms 1Optic Nerve Glioma 1Neuroectodermal Tumors, Primitive 1Neoplasms 1Mouth Neoplasms 1Mesothelioma 1Lymphoma 1Liver Neoplasms 1Liposarcoma 1

Interventions

Cisplatin 3sodium thiosulfate 2Acetylcysteine 2Vorinostat 1Surveys and Questionnaires 1Radiosurgery 1Pantoprazole 1Methotrexate 1Hydroxymethylglutaryl-CoA Reductase Inhibitors 1Hearing Tests 1Genetic Association Studies 1Dexamethasone 1Audiometry 1Atorvastatin 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
OTHER × Ototoxicity × sodium thiosulfate × Clear all
NCT05756660 2025-10-20

Sodium Thiosulfate Otoprotection During Salvage Cisplatin Therapy

Children's Hospital Medical Center, Cincinnati

Phase EARLY_PHASE1 Suspended
33 enrolled
Gastrointestinal

Ototoxicity, Neoplasms, Germ Cell and Embryonal, Hepatoblastoma

NCT00652132 2018-05-29

SIOPEL6

University of Birmingham

Phase 3 Completed
116 enrolled 1 FDA
Gastrointestinal

Ototoxicity, Liver Neoplasms, Hepatoblastoma

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