Announcements Trials
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Phase

Phase 1/2 3

Status

Terminated 2Completed 1

Sponsor Class

INDUSTRY 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

Gastrointestinal 3Thoracic 1Gynecologic 1

Conditions

Melanoma 20Neoplasm Metastasis 8Leukemia, Myeloid, Acute 7Skin Neoplasms 6Ovarian Neoplasms 6Lymphoma, Non-Hodgkin 6Colorectal Neoplasms 6Carcinoma, Non-Small-Cell Lung 6Leukemia, Lymphocytic, Chronic, B-Cell 5Uveal Melanoma 4Stomach Neoplasms 4Squamous Cell Carcinoma of Head and Neck 4Neoplasms 4Triple Negative Breast Neoplasms 3Recurrence 3Rectal Neoplasms 3Pancreatic Neoplasms 3Mesothelioma, Malignant 3Lymphoma, Follicular 3Lymphoma 3Lung Neoplasms 3Leukemia 3Esophageal Neoplasms 3Carcinoma, Renal Cell 3Uterine Cervical Neoplasms 2Sarcoma 2Pleural Effusion, Malignant 2Neuroblastoma 2Myelodysplastic Syndromes 2Multiple Myeloma 2

Interventions

Gemcitabine 113130-nm albumin-bound paclitaxel 64Albumin-Bound Paclitaxel 43Fluorouracil 37Magnetic Resonance Spectroscopy 35pembrolizumab 34Irinotecan 34Taxes 33Specimen Handling 33Leucovorin 33Oxaliplatin 31Biopsy 22Cyclophosphamide 21Nivolumab 18fludarabine 16Radiosurgery 16Cisplatin 16Drug Therapy 15Capecitabine 12folfirinox 11durvalumab 11Radiotherapy 11irinotecan sucrosofate 10Ipilimumab 10Cetuximab 10Carboplatin 10Blood Specimen Collection 10olaparib 9Standard of Care 9dehydroftorafur 8

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Pancreatic Neoplasms × Interleukin-2 × 1 year × Clear all
NCT03745326 2026-05-19

Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients

National Institutes of Health Clinical Center (CC)

Phase 1/2 Terminated
5 enrolled 14 charts
Gastrointestinal

Colonic Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT04426669 2026-02-23

A Study of Metastatic Gastrointestinal Cancers Treated With Tumor Infiltrating Lymphocytes in Which the Gene Encoding the Intracellular Immune Checkpoint CISH Is Inhibited Using CRISPR Genetic Engineering

Intima Bioscience, Inc.

Phase 1/2 Completed
23 enrolled
Gastrointestinal

Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

NCT05194735 2025-11-10

Phase I/II Study of Autologous T Cells to Express T-Cell Receptors (TCRs) in Subjects With Solid Tumors

Alaunos Therapeutics

Phase 1/2 Terminated
8 enrolled 12 charts
GastrointestinalGynecologicThoracic

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

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