Clinical Trials

405 enrolled

Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT07252232 2026-06-04

RASolute 304

500 enrolled

Pancreatic Neoplasms

NCT07562152 2026-06-04

MAPKeeper 301

510 enrolled

Neoplasm Metastasis, Pancreatic Neoplasms

NCT07627711 2026-06-04

DUAL-NK-PDAC

42 enrolled

Neoplasm Metastasis, Pancreatic Neoplasms

NCT05546476 2026-06-03

PROACC-1

Phase 2 Completed

187 enrolled 24 charts

Anorexia, Cachexia, Carcinoma, Non-Small-Cell Lung, Fatigue, Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Weight Loss

NCT06040541 2026-06-03

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

604 enrolled

Phase 2/3 Active not recruiting

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Gastrointestinal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Colorectal Neoplasms

NCT07076121 2026-06-03

A Study Comparing Navlimetostat (BMS-986504) in Combination With Nab-paclitaxel and Gemcitabine Versus Placebo in Combination With Nab-paclitaxel and Gemcitabine in Participants With Untreated Metastatic Pancreatic Ductal Adenocarcinoma With Homozygous MTAP Deletion (MountainTAP-30)

470 enrolled

Pancreatic Neoplasms

NCT07491445 2026-06-03

RASolute 303

900 enrolled

Pancreatic Neoplasms

NCT04104672 2026-06-02

ARC-8

196 enrolled

BreastGastrointestinalGenitourinaryGynecologicOther solid neoplasmThoracic

Pancreatic Neoplasms

NCT04981119 2026-06-02

BASECAMP-1

Recruiting

200 enrolled

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Kidney Neoplasms, Mesothelioma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT05417594 2026-06-02

CERTIS1

BreastCNSGastrointestinalGenitourinaryGynecologic

695 enrolled

Astrocytoma, Breast Neoplasms, Fallopian Tube Neoplasms, Glioma, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms

NCT05663515 2026-06-02

EXCEED

Recruiting

24,000 enrolled

Phase 3 Active not recruiting

Pancreatic Neoplasms

NCT06608927 2026-06-02

PRISM-1

610 enrolled

Phase 3 Active not recruiting

Pancreatic Neoplasms

NCT06625320 2026-06-02

RASolute 302

500 enrolled

Pancreatic Neoplasms

NCT07409272 2026-06-02

A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer

614 enrolled

Pancreatic Neoplasms

NCT07621718 2026-06-02

RASolute 305

670 enrolled

Pancreatic Neoplasms

NCT06360354 2026-06-01

MTAPESTRY 103

120 enrolled

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

Neoplasms, Pancreatic Neoplasms

NCT07124000 2026-06-01

DP-04

Recruiting

100 enrolled

Adenocarcinoma, Anus Neoplasms, Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Melanoma, Mouth Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Salivary Gland Neoplasms, Sarcoma, Testicular Neoplasms, Thyroid Neoplasms, Urethral Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Endometrial Neoplasms, Gastrointestinal Stromal Tumors, Small Cell Lung Carcinoma

NCT07349537 2026-06-01

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

574 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT07522073 2026-06-01

DAWN-303

588 enrolled

Phase 1/2 Active not recruiting

Pancreatic Neoplasms

NCT04956640 2026-05-29

Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

540 enrolled

GastrointestinalGynecologicThoracic

Biliary Tract Neoplasms, Carcinoma, Non-Small-Cell Lung, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT07492680 2026-05-29

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

Phase 2 Not yet recruiting

260 enrolled

CNSDermatologicGastrointestinal

Brain Neoplasms, Melanoma, Pancreatic Neoplasms

NCT06361888 2026-05-28

A Phase II/III Trial to Evaluate the Efficacy and Safety of Surufatinib Combined With Camrelizumab, Nab-paclitaxel, and Gemcitabine in Metastatic Pancreatic Cancer

Phase 2/3 Recruiting

502 enrolled

Phase 1/2 Active not recruiting

Pancreatic Neoplasms

NCT06710132 2026-05-28

Study of Anti-CEACAM5 ADC M9140 in Participants With Advanced Solid Tumors (PROCEADE PanTumor)

250 enrolled

Carcinoma, Non-Small-Cell Lung, Pancreatic Neoplasms, Stomach Neoplasms

NCT07223047 2026-05-28

A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies

252 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT07589569 2026-05-28

An Open-label, Multicenter, Phase II Clinical Study to Evaluate HRS-7058 in Patients With Pancreatic Cancer

Phase 2 Recruiting

92 enrolled

Pancreatic Neoplasms

NCT07605819 2026-05-28

ENZEAVOUR FS

Phase NA Recruiting

10,000 enrolled

Phase 2 Active not recruiting

Pancreatic Neoplasms

NCT02568267 2026-05-27

STARTRK-2

534 enrolled 1 FDA

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidNETSarcomaThoracic

Thyroid Cancer, Papillary, Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Head and Neck Neoplasms, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Salivary Gland Neoplasms, Sarcoma, Colorectal Neoplasms, Lymphoma, Large-Cell, Anaplastic, Cholangiocarcinoma, Neuroendocrine Tumors

NCT06051695 2026-05-26

EVEREST-2

GastrointestinalGynecologicOther solid neoplasmThoracic

474 enrolled

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Recurrence, Colorectal Neoplasms

NCT06607185 2026-05-26

A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

GastrointestinalGynecologicThoracic

750 enrolled

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT06238479 2026-05-22

EXCEED

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

490 enrolled

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Ureteral Neoplasms, Urologic Neoplasms, Triple Negative Breast Neoplasms

NCT06465069 2026-05-22

NEXUS-01

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

420 enrolled

NCT06868849 2026-05-22

A Study of JMT203 in Patients With Cancer Cachexia

307 enrolled

Carcinoma, Non-Small-Cell Lung, Pancreatic Neoplasms

NCT06673017 2026-05-20

PTM-101 in Pancreatic Ductal Adenocarcinoma (PDAC)

26 enrolled

BreastGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Pancreatic Neoplasms

NCT06885424 2026-05-20

DESCENT-1

Enrolling by invitation

400 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Head and Neck Neoplasms, Kidney Neoplasms, Mesothelioma, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT07597772 2026-05-19

Preliminary Trial of SNA014 for Pancreatic Cancer

Phase EARLY_PHASE1 Recruiting

12 enrolled

Pancreatic Neoplasms

NCT04421820 2026-05-18

BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours

220 enrolled

Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT05379985 2026-05-15

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

DermatologicGastrointestinalThoracic

754 enrolled

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Gastrointestinal Neoplasms, Intestinal Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplastic Processes, Pancreatic Neoplasms, Thoracic Neoplasms, Colorectal Neoplasms, Carcinoma, Pancreatic Ductal

NCT05462717 2026-05-15

Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors