Announcements Trials
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Phase

Phase 1/2 1

Status

Recruiting 1

Sponsor Class

OTHER 3NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1

Conditions

Carcinoma, Non-Small-Cell Lung 48Breast Neoplasms 48Lung Neoplasms 34Ovarian Neoplasms 33Fallopian Tube Neoplasms 22Carcinoma, Ovarian Epithelial 21Adenocarcinoma of Lung 16Unspecified Adult Solid Tumor, Protocol Specific 13Brenner Tumor 11Adenocarcinoma, Bronchiolo-Alveolar 11Head and Neck Neoplasms 10Breast Neoplasms, Male 10Neoplasm Metastasis 9Uterine Cervical Neoplasms 7Triple Negative Breast Neoplasms 7Squamous Cell Carcinoma of Head and Neck 7Neoplasms 7Esophageal Neoplasms 7Endometrial Neoplasms 7Adenocarcinoma Of Esophagus 6Urinary Bladder Neoplasms 5Oropharyngeal Neoplasms 5Melanoma 5Precursor Cell Lymphoblastic Leukemia-Lymphoma 4Peritoneal Neoplasms 4Mouth Neoplasms 4Lymphoma, Non-Hodgkin 4Lymphoma, Mantle-Cell 4Lymphoma, Large-Cell, Immunoblastic 4Lymphoma, Large B-Cell, Diffuse 4

Interventions

durvalumab 1Pemetrexed 1Paclitaxel 1Gemcitabine 1Cisplatin 1Carboplatin 1Azacitidine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
NIH × Pathologic Complete Response × Paclitaxel × Clear all
NCT06694454 2026-06-04

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

National Institutes of Health Clinical Center (CC)

Phase 1/2 Recruiting
60 enrolled
Thoracic

Pathologic Complete Response, Carcinoma, Non-Small-Cell Lung

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