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Phase

Phase 1/2 1

Status

Completed 3Recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Lymphoid 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 55Leukemia, Myeloid, Acute 38Breast Neoplasms 38Lymphoma, Large B-Cell, Diffuse 35Multiple Myeloma 31Lymphoma, Non-Hodgkin 29Burkitt Lymphoma 29Lymphoma 27Myelodysplastic Syndromes 25Triple Negative Breast Neoplasms 23Recurrence 23Hematologic Neoplasms 22Lymphoma, B-Cell 21Lymphoma, Follicular 20Melanoma 16Ovarian Neoplasms 15Leukemia, Lymphocytic, Chronic, B-Cell 15Neoplasm Metastasis 14Leukemia 14Hodgkin Disease 13Neoplasms 12Leukemia, Biphenotypic, Acute 12Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 11Pancreatic Neoplasms 11Neuroblastoma 11Leukemia, Myelomonocytic, Chronic 11Lymphoma, Mantle-Cell 10Graft vs Host Disease 10Carcinoma, Non-Small-Cell Lung 10Lymphoma, T-Cell, Peripheral 9

Interventions

olverembatinib 1fludarabine 1blinatumomab 1Prednisone 1N-(2-amino-5-fluorobenzyl)-4-(N-(pyridine-3-acrylyl)aminomethyl)benzamide 1Cyclophosphamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Recruiting × Philadelphia Chromosome × Cyclophosphamide × Clear all
NCT05442515 2026-05-28

CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies

National Institutes of Health Clinical Center (CC)

Phase 1/2 Recruiting
130 enrolled
LymphoidOther hematologic neoplasm

Burkitt Lymphoma, Lymphoma, Lymphoma, Non-Hodgkin, Philadelphia Chromosome, Leukemia, B-Cell, Lymphoma, B-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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