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Phase

Phase 1/2 1Phase 1 1

Status

Completed 1

Sponsor Class

INDUSTRY 3OTHER 2NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Lymphoid 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 136Unspecified Adult Solid Tumor, Protocol Specific 122Leukemia, Lymphocytic, Chronic, B-Cell 119Lymphoma 103Breast Neoplasms 102Neoplasms 99Lymphoma, Follicular 98Burkitt Lymphoma 98Lymphoma, Large B-Cell, Diffuse 97Lymphoma, Non-Hodgkin 94Leukemia, Myeloid, Acute 89Lymphoma, Mantle-Cell 88Lymphoma, B-Cell, Marginal Zone 81Neoplasm Metastasis 80Lymphoma, Large-Cell, Immunoblastic 73Carcinoma, Non-Small-Cell Lung 68Melanoma 64Hodgkin Disease 64Lymphoma, T-Cell, Cutaneous 63Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 60Lymphoma, Large-Cell, Anaplastic 60Lung Neoplasms 60Prostatic Neoplasms 58Brain Neoplasms 58Astrocytoma 57Mycosis Fungoides 55Colonic Neoplasms 55Glioblastoma 54Sezary Syndrome 52Ovarian Neoplasms 52

Interventions

fludarabine phosphate 1fludarabine 1Magnetic Resonance Imaging 1Electrocardiography 1Echocardiography 1Diphenhydramine 1Cyclophosphamide 1Blood Component Removal 1Antiemetics 1Acetaminophen 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1 × NIH × Philadelphia Chromosome × Clear all
NCT03448393 2025-06-04

CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
54 enrolled 24 charts
LymphoidOther hematologic neoplasm

Burkitt Lymphoma, Lymphoma, Lymphoma, Non-Hodgkin, Philadelphia Chromosome, Leukemia, B-Cell, Lymphoma, B-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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