Announcements Trials
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Phase

Phase 1 1

Status

Recruiting 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1CNS 1

Conditions

Meningioma 2Glioblastoma 2Ependymoma 2Central Nervous System Neoplasms 2Typical Teratoid Rhabdoid Tumor 1Pinealoma 1Paraganglioma 1Oligodendroglioma 1Neuroectodermal Tumors, Primitive 1Neuroectodermal Tumors 1Neoplasms, Neuroepithelial 1Medulloblastoma 1Gliosarcoma 1Glioma 1Choroid Plexus Neoplasms 1Astrocytoma 1

Interventions

Cyclophosphamide 4Automobiles 3fludarabine 2etoposide phosphate 2Nivolumab 2Etoposide 2Celecoxib 2perillyl alcohol 1omburtamab I-131 1Watchful Waiting 1Vincristine 1Thiotepa 1Temozolomide 1Tamoxifen 1Sirolimus 1Proton Therapy 1ONC206 1Mesna 1Isotretinoin 1Immunotherapy 1Hydrocortisone 1Granulocyte Colony-Stimulating Factor 1Filgrastim 1Cisplatin 1Carboplatin 1

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
Pinealoma × ONC206 × 1 year × Clear all
NCT04541082 2025-12-18

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

Jazz Pharmaceuticals

Phase 1 Recruiting
102 enrolled
CNSSarcoma

Typical Teratoid Rhabdoid Tumor, Astrocytoma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Oligodendroglioma, Pinealoma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma

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