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Phase

Phase 2 1Phase 1/2 1

Status

Withdrawn 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Gynecologic 1

Conditions

Breast Neoplasms 32Carcinoma, Non-Small-Cell Lung 29Leukemia, Myeloid, Acute 27Melanoma 25Neoplasms 22Lymphoma 21Pancreatic Neoplasms 18Multiple Myeloma 18Recurrence 17Lung Neoplasms 17Leukemia 17Ovarian Neoplasms 16Neoplasm Metastasis 15Lymphoma, Non-Hodgkin 15Carcinoma, Hepatocellular 15Colorectal Neoplasms 14Lymphoma, Follicular 13Myelodysplastic Syndromes 12Lymphoma, B-Cell 12Leukemia, Lymphocytic, Chronic, B-Cell 12Burkitt Lymphoma 12Precursor Cell Lymphoblastic Leukemia-Lymphoma 11Lymphoma, Large B-Cell, Diffuse 11Prostatic Neoplasms 10Lymphoma, Mantle-Cell 10Brain Neoplasms 10Stomach Neoplasms 9Squamous Cell Carcinoma of Head and Neck 9Liver Neoplasms 9Glioma 9

Interventions

Taxes 1Specimen Handling 1Paclitaxel 1Magnetic Resonance Spectroscopy 1Immunoglobulin G 1Disulfides 1Bevacizumab 1ASTX-660 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1/2 × Withdrawn × Platinum-Refractory Fallopian Tube Carcinoma × Clear all
NCT06393751 2025-06-03

Testing the Addition of ASTX660 (Tolinapant) to the Usual Chemotherapy Treatment (Paclitaxel With or Without Bevacizumab) in Patients With Recurrent Ovarian Cancer

National Cancer Institute (NCI)

Phase 1/2 Withdrawn
GynecologicSarcoma

Platinum-Refractory Fallopian Tube Carcinoma

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