Clinical Trials Browser

Interventional × Pleural Effusion, Malignant × 1 year × Clear all

NCT00761618 2026-04-16

Intrapleural Catheter Daily Versus Three Times a Week Drainage

Phase 2 Active not recruiting

Pleural Effusion, Pleural Effusion, Malignant

NCT07443020 2026-04-07

RIOT 4B

Phase 1 Recruiting

Other solid neoplasmThoracic

Mesothelioma, Malignant, Pleural Effusion, Malignant

NCT02122185 2026-03-27

Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Phase 2 Completed

111 enrolled 15 charts

GynecologicThoracic

Carcinoma, Ovarian Epithelial, Brenner Tumor, Fallopian Tube Neoplasms, Pleural Effusion, Malignant

NCT06097962 2026-03-20

Safety and Efficacy of NK510 to Treat NSCLC

Phase EARLY_PHASE1 Recruiting

Pleural Effusion, Malignant

NCT07482605 2026-03-20

Furmonertinib Plus Radiotherapy for EGFR+ NSCLC With Pleural Effusion

Phase 2 Not yet recruiting

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Pleural Effusion, Malignant

NCT07192900 2026-01-15

(RIOT 4A)

Phase 1 Recruiting

Other solid neoplasmThoracic

Mesothelioma, Malignant, Pleural Effusion, Malignant

NCT07332858 2026-01-14

First-in-Human Expanded Cohort Study of Intrapleural Administration of TolueneSulfonamide in Patients With Malignant Pleural Effusion

Phase 1/2 Not yet recruiting

MyeloidThoracic

Myeloproliferative Disorder, Chronic, with Eosinophilia, Carcinoma, Non-Small-Cell Lung, Pleural Effusion, Malignant

NCT07167992 2026-01-06

Comparison of Talc Slurry Versus Talc Insufflation: A Study on Effectiveness, Safety, and Hospital Outcomes in Pleurodesis

Phase NA Not yet recruiting

Pneumothorax, Pleural Effusion, Malignant

NCT04914598 2026-01-02

A Phase Ⅲ Clinical Study of Combined Cisplatin Versus Placebo Combined With Intracavitary Cisplatin Injection in the Treatment of Malignant Pleural Effusions

Phase 3 Active not recruiting

Pleural Effusion, Malignant

NCT07208409 2025-12-24

Pleurodesis in Small-bore Chest Tube

Phase NA Not yet recruiting

Pleural Effusion, Malignant

NCT02649894 2025-12-11

SWIFT

Phase NA Completed

119 enrolled 16 charts

Pleural Effusion, Malignant

NCT02227732 2025-11-26

A Pilot Study Evaluating the Safety and Effectiveness of a New Pleural Catheter for the Medical Management of Symptomatic, Recurrent, Malignant Pleural Effusions

Phase NA Completed

Pleural Effusion, Malignant

NCT07147270 2025-08-29

Impact of Patient Position on Chemical Pleurodesis by Chest Ultrasound

Phase NA Recruiting

Pleural Effusion, Malignant

NCT07120867 2025-08-13

Impact of Pleural Manometry on the Assessment and Treatment of Malignant Pleural Effusion: A Pilot Clinical Trial

Phase NA Recruiting

MyeloidThoracic

Myeloproliferative Disorder, Chronic, with Eosinophilia, Pleural Effusion, Malignant

NCT06210685 2025-08-11

The ACES Study for Aseptic Pleural Effusion

Phase NA Active not recruiting

Pleural Effusion, Pleural Effusion, Malignant

NCT05543330 2025-07-20

A Phase Ib/II Clinical Trial of M701 in the Treatment of Malignant Pleural Effusions Caused by NSCLC

Phase 1/2 Recruiting

Carcinoma, Non-Small-Cell Lung, Pleural Effusion, Malignant

NCT06016179 2025-05-22

RIOT2

Phase 1 Recruiting

Pleural Effusion, Malignant

NCT06964321 2025-05-09

Effectiveness of Intercostal Tube Drainage Vs Pigtail Catheter Drainage Vs Ultrasound-Guided Aspiration in Management of Massive Malignant Pleural Effusion

Phase NA Not yet recruiting

Pleural Effusion, Malignant

NCT06959719 2025-05-07

ARMSTRONG

Phase NA Recruiting

MyeloidThoracic

Myeloproliferative Disorder, Chronic, with Eosinophilia, Pleural Effusion, Pleural Effusion, Malignant

NCT06946498 2025-04-27

FLAT

Phase NA Recruiting

Other solid neoplasmThoracic

Mesothelioma, Malignant, Lung Neoplasms, Mesothelioma, Pleural Effusion, Pleural Effusion, Malignant