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Phase

Phase 3 1

Status

Recruiting 1

Sponsor Class

NETWORK 1

Study Type

Interventional 1

Sponsor

Conditions

Sarcoma 17Rhabdomyosarcoma 14Wilms Tumor 9Malignant mesenchymal tumor 7Gestational Trophoblastic Disease 6Kidney Neoplasms 5Neuroectodermal Tumors, Primitive, Peripheral 4Rhabdomyosarcoma, Embryonal 3Melanoma 3Fibrosarcoma 3Sarcoma, Ewing 2Rhabdomyosarcoma, Alveolar 2Ovarian Neoplasms 2Liposarcoma 2Hydatidiform Mole 2Hemangiosarcoma 2Hemangiopericytoma, Malignant 2Desmoplastic Small Round Cell Tumor 2Choriocarcinoma 2Testicular Neoplasms 1Teratoma, Ovarian 1Stage I Mixed Cell Type Kidney Wilms Tumor 1Sarcoma, Alveolar Soft Part 1Rhabdoid Tumor 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Pleuropulmonary blastoma 1Neoplasms, Germ Cell and Embryonal 1Neoplasms 1Lymphoma 1Leukemia, Myelogenous, Chronic, BCR-ABL Positive 1

Interventions

lorvotuzumab mertansine 1Watchful Waiting 1Vincristine 1Topotecan 1Specimen Handling 1Razoxane 1Observation 1Magnetic Resonance Spectroscopy 1Ifosfamide 1High-Energy Shock Waves 1Doxorubicin 1Dexrazoxane 1Dactinomycin 1Cyclophosphamide 1Ado-Trastuzumab Emtansine 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Interventional × Pleuropulmonary blastoma × Dactinomycin × Clear all
NCT06647953 2026-05-05

Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

Children's Oncology Group

Phase 3 Recruiting
110 enrolled

Pleuropulmonary blastoma

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