Announcements Trials
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Phase

Phase 2 1Phase 1/2 1

Status

Completed 1Active not recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Myeloid 2Other hematologic neoplasm 1

Conditions

Leukemia, Myeloid, Acute 160Myelodysplastic Syndromes 44Leukemia, Myelomonocytic, Chronic 25Leukemia 16Myeloproliferative Disorders 11Recurrence 9Hematologic Neoplasms 8Neoplasms 6Lymphoma, T-Cell, Peripheral 6Primary Myelofibrosis 5Leukemia, Biphenotypic, Acute 5Anemia, Refractory, with Excess of Blasts 5Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 4Neoplasm, Residual 4Multiple Myeloma 4Lymphoma, Non-Hodgkin 4Leukemia, Monocytic, Acute 4Hematologic Diseases 4GATA2 Deficiency 4Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Pathologic Complete Response 3Pancreatic Neoplasms 3Neoplasm Metastasis 3Myelodysplastic-Myeloproliferative Diseases 3Lymphoma 3Hodgkin Disease 3Carcinoma, Non-Small-Cell Lung 3Breast Neoplasms 3Polycythemia Vera 2Lymphoma, T-Cell 2

Interventions

ruxolitinib 10fludarabine phosphate 5Whole-Body Irradiation 5Cyclophosphamide 5Tacrolimus 4Peripheral Blood Stem Cell Transplantation 4Mycophenolic Acid 4Hydroxyurea 4bomedemstat 3Stem Cell Transplantation 3Specimen Handling 3Busulfan 3Biopsy 3Aspirin 3fludarabine 2Phlebotomy 2Methotrexate 2Melphalan 2Injections 2Azacitidine 2venetoclax 1veliparib 1umbralisib 1piperine 1pevonedistat 1methanesulfonic acid 1itacitinib 1iadademstat 1givinostat hydrochloride 1givinostat 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Polycythemia Vera × Azacitidine × 1 year × Clear all
NCT01787487 2026-03-31

Ruxolitinib Phosphate and Azacytidine in Treating Patients With Myelofibrosis or Myelodysplastic Syndrome/Myeloproliferative Neoplasm

M.D. Anderson Cancer Center

Phase 2 Completed
121 enrolled
Myeloid

Myeloproliferative Disorders, Polycythemia Vera, Primary Myelofibrosis

NCT03862157 2026-03-11

Azacitidine, Venetoclax, and Pevonedistat in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

M.D. Anderson Cancer Center

Phase 1/2 Active not recruiting
40 enrolled
MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Myeloproliferative Disorders, Polycythemia Vera, Thrombocythemia, Essential, Thrombocytosis, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hypereosinophilic Syndrome, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

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