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Phase

Phase 1/2 1

Status

Terminated 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Myeloid 1

Conditions

Leukemia, Myeloid, Acute 68Burkitt Lymphoma 17Precursor Cell Lymphoblastic Leukemia-Lymphoma 16Leukemia, Biphenotypic, Acute 14Myelodysplastic Syndromes 12Leukemia 8Myeloproliferative Disorders 7Lymphoma, Mantle-Cell 7Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 6Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 6Recurrence 4Lymphoma, Non-Hodgkin 4Lymphoma 4Leukemia, Myelomonocytic, Chronic 4Blast Crisis 4Sarcoma, Myeloid 3Leukemia, Monocytic, Acute 3Down Syndrome 3Lymphoma, T-Cell 2Lymphoma, Large B-Cell, Diffuse 2Lymphoma, Follicular 2Leukemia, Myelomonocytic, Juvenile 2Leukemia, Myelomonocytic, Acute 2Leukemia, Myeloid, Accelerated Phase 2Leukemia, Myeloid 2Hodgkin Disease 2Hematologic Neoplasms 2Anemia, Refractory, with Excess of Blasts 2Thrombocythemia, Essential 1Targeted Therapy 1

Interventions

ruxolitinib 6Hydroxyurea 3fludarabine phosphate 2bomedemstat 2Whole-Body Irradiation 2Tacrolimus 2Specimen Handling 2Peripheral Blood Stem Cell Transplantation 2Mycophenolic Acid 2Injections 2Cyclophosphamide 2Busulfan 2Biopsy 2veliparib 1umbralisib 1piperine 1iadademstat 1givinostat hydrochloride 1givinostat 1fludarabine 1fedratinib 1demethoxycurcumin 1decitabine and cedazuridine drug combination 1Transplantation 1Topotecan 1Stem Cell Transplantation 1Sirolimus 1Resistance Training 1Radiotherapy 1Panobinostat 1

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
Polycythemia Vera × Cytarabine × 90 days × Clear all
NCT03878199 2026-04-24

Testing the Effect of Taking Ruxolitinib and CPX-351 in Combination for the Treatment of Advanced Phase Myeloproliferative Neoplasms

Ohio State University Comprehensive Cancer Center

Phase 1/2 Terminated
12 enrolled 15 charts
Myeloid

Myeloproliferative Disorders, Polycythemia Vera, Thrombocythemia, Essential, Primary Myelofibrosis

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