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Phase

Phase 2 2Phase 1/2 2Phase 1 2

Status

Terminated 1Completed 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Myeloid 2Other hematologic neoplasm 1Lymphoid 1Classical hematology 1

Conditions

Leukemia, Myeloid, Acute 81Leukemia 33Precursor Cell Lymphoblastic Leukemia-Lymphoma 25Myelodysplastic Syndromes 22Recurrence 13Congenital Abnormalities 12Lymphoma, Non-Hodgkin 9Leukemia, Biphenotypic, Acute 9Burkitt Lymphoma 9Lymphoma, Mantle-Cell 8Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 7Leukemia, Myelomonocytic, Chronic 7Leukemia, Monocytic, Acute 7Hodgkin Disease 7Lymphoma 6Leukemia, Myelomonocytic, Acute 6Leukemia, Megakaryoblastic, Acute 6Leukemia, Erythroblastic, Acute 6Lymphoma, Large B-Cell, Diffuse 5Leukemia, Myelogenous, Chronic, BCR-ABL Positive 5Myeloproliferative Disorders 4Lymphoma, Follicular 4Lymphoma, B-Cell 4Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 3Neoplasms 3Leukemia, Prolymphocytic 3Leukemia, Myeloid 3Leukemia, Lymphocytic, Chronic, B-Cell 3Hematologic Neoplasms 3Blast Crisis 3

Interventions

Peripheral Blood Stem Cell Transplantation 7Busulfan 5ruxolitinib 4Methotrexate 4Cyclosporine 4fludarabine phosphate 3Whole-Body Irradiation 2Mycophenolic Acid 2Flow Cytometry 2Cytogenetic Analysis 2Cytarabine 2Cyclophosphamide 2Antilymphocyte Serum 2venetoclax 1sonidegib 1pomalidomide 1pevonedistat 1pelcitoclax 1lestaurtinib 1givinostat hydrochloride 1givinostat 1ethanolamine oleate 1aldesleukin 1Vitamin E 1Trimethoprim, Sulfamethoxazole Drug Combination 1Trimethoprim 1Transplantation 1Topotecan 1Tacrolimus 1Sulfamethoxazole 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1/2 × Polycythemia Vera × Cytarabine × Clear all
NCT03878199 2026-04-24

Testing the Effect of Taking Ruxolitinib and CPX-351 in Combination for the Treatment of Advanced Phase Myeloproliferative Neoplasms

Ohio State University Comprehensive Cancer Center

Phase 1/2 Terminated
12 enrolled 15 charts
Myeloid

Myeloproliferative Disorders, Polycythemia Vera, Thrombocythemia, Essential, Primary Myelofibrosis

NCT00003619 2013-06-26

Combination Chemotherapy Followed By Peripheral Stem Cell Transplantation or Isotretinoin in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Acute Lymphocytic Leukemia

National Cancer Institute (NCI)

Phase 1/2 Completed
Classical hematologyLymphoidMyeloidOther hematologic neoplasm

Anemia, Refractory, Anemia, Refractory, with Excess of Blasts, Blast Crisis, Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Polycythemia Vera, Thrombocytopenia, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Primary Myelofibrosis

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