Announcements Trials
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Phase

Phase 1/2 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other neoplasm 1Other hematologic neoplasm 1Myeloid 1

Conditions

Primary Myelofibrosis 4Leukemia, Myeloid, Acute 4Myelodysplastic Syndromes 3Polycythemia Vera 2Neoplasms 2Myeloproliferative Disorders 2Lymphoma, T-Cell 2Leukemia 2Graft vs Host Disease 2Thrombocythemia, Essential 1Thalassemia 1Preleukemia 1Precancerous Conditions 1Neoplasms by Histologic Type 1Myelodysplastic-Myeloproliferative Diseases 1Mycosis Fungoides 1Multiple Myeloma 1Lymphoma, T-Cell, Cutaneous 1Lymphoma, Large-Cell, Anaplastic 1Lymphoma, B-Cell 1Leukemia, Myelogenous, Chronic, BCR-ABL Positive 1Immunoblastic Lymphadenopathy 1Hematologic Neoplasms 1Hematologic Diseases 1Glioma 1Glioblastoma 1Carcinoma, Non-Small-Cell Lung 1Bronchiolitis Obliterans Syndrome 1Bone Marrow Diseases 1

Interventions

ruxolitinib 1fludarabine phosphate 1Whole-Body Irradiation 1Tacrolimus 1Sirolimus 1Robotic Surgical Procedures 1Peripheral Blood Stem Cell Transplantation 1Mycophenolic Acid 1Methotrexate 1Melphalan 1Hysterectomy 1Etoposide 1Cyclosporine 1Cyclophosphamide 1CPI-0610 1Busulfan 1Blood Specimen Collection 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Precancerous Conditions × ruxolitinib × 30 days × Clear all
NCT02158858 2026-06-04

A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative Malignancies

Constellation Pharmaceuticals

Phase 1/2 Completed
336 enrolled 61 charts
MyeloidOther hematologic neoplasmOther neoplasm

Bone Marrow Diseases, Hematologic Diseases, Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasms, Neoplasms by Histologic Type, Precancerous Conditions, Preleukemia, Thrombocythemia, Essential, Leukemia, Myeloid, Acute, Myelodysplastic-Myeloproliferative Diseases, Primary Myelofibrosis

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