Announcements Trials
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Phase

Phase 1 2

Status

Suspended 1Recruiting 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Plasma cell 2Other hematologic neoplasm 2Myeloid 2Lymphoid 2Gastrointestinal 1

Conditions

Melanoma 15Neoplasm Metastasis 11Ovarian Neoplasms 9Pancreatic Neoplasms 8Carcinoma, Non-Small-Cell Lung 8Stomach Neoplasms 6Skin Neoplasms 6Leukemia, Myeloid, Acute 6Colorectal Neoplasms 6Carcinoma, Renal Cell 6Triple Negative Breast Neoplasms 4Gastrointestinal Neoplasms 4Breast Neoplasms 4Vulvar Neoplasms 3Uterine Cervical Neoplasms 3Urogenital Neoplasms 3Rectal Neoplasms 3Neuroblastoma 3Myelodysplastic Syndromes 3Multiple Myeloma 3Leukemia 3Colonic Neoplasms 3Vaginal Neoplasms 2Squamous Cell Carcinoma of Head and Neck 2Sarcoma 2Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Pleural Effusion, Malignant 2Penile Neoplasms 2Oropharyngeal Neoplasms 2Neoplasms 2

Interventions

Cyclophosphamide 103fludarabine 61Methotrexate 49Dexamethasone 46fludarabine phosphate 45Cytarabine 45Vincristine 42blinatumomab 36Whole-Body Irradiation 33Mycophenolic Acid 30Tacrolimus 26Mercaptopurine 26Melphalan 26venetoclax 24Specimen Handling 24Etoposide 23Peripheral Blood Stem Cell Transplantation 21pegaspargase 20Stem Cell Transplantation 19Granulocyte Colony-Stimulating Factor 19Calcium Dobesilate 19Busulfan 19Doxorubicin 18Prednisone 17Rituximab 16Filgrastim 16Daunorubicin 16Asparaginase 16merphos 15Thiotepa 15

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Precursor Cell Lymphoblastic Leukemia-Lymphoma × aldesleukin × 1 year × Clear all
NCT06904066 2026-06-05

Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies

National Institutes of Health Clinical Center (CC)

Phase 1 Recruiting
86 enrolled
LymphoidMyeloidOther hematologic neoplasmPlasma cell

Multiple Myeloma, Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT05400122 2025-11-12

Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer

Case Comprehensive Cancer Center

Phase 1 Suspended
12 enrolled
GastrointestinalLymphoidMyeloidOther hematologic neoplasmPlasma cell

Esophageal Neoplasms, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Neoplasm Metastasis, Rectal Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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