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Phase

Phase 1 1

Status

Withdrawn 1

Sponsor Class

OTHER 17INDUSTRY 4NIH 2NETWORK 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Other hematologic neoplasm 1Lymphoid 1CNS 1

Conditions

Squamous Cell Carcinoma of Head and Neck 4Breast Neoplasms 4Sarcoma 2Ovarian Neoplasms 2Lymphoma, Large-Cell, Anaplastic 2Lymphoma, Large B-Cell, Diffuse 2Lung Neoplasms 2Head and Neck Neoplasms 2Central Nervous System Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Burkitt Lymphoma 2Astrocytoma 2Spinal Cord Neoplasms 1Recurrence 1Radiation Injuries 1Radiation Fibrosis Syndrome 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Optic Nerve Glioma 1Medulloblastoma 1Lymphoma, T-Cell 1Lymphoma, Non-Hodgkin 1Lymphoma, Large-Cell, Immunoblastic 1Lymphoma, Follicular 1Lymphoma, Extranodal NK-T-Cell 1Lymphoma, AIDS-Related 1Lymphoma 1Lymphedema 1Localized Advanced Rectal Adenocarcinoma 1Leukemia, Myelomonocytic, Juvenile 1Leukemia, Myelomonocytic, Acute 1

Interventions

Methotrexate 29Cytarabine 28Vincristine 26Cyclophosphamide 25Mercaptopurine 20Dexamethasone 20pegaspargase 18Prednisone 17Doxorubicin 17Daunorubicin 16Asparaginase 15merphos 14Calcium Dobesilate 14Thioguanine 13Leucovorin 13Radiotherapy 11Hydrocortisone 10azathiopurine 9Filgrastim 9Etoposide 9Granulocyte Colony-Stimulating Factor 8dexamethasone acetate 7dexamethasone 21-phosphate 7auricularum 7Specimen Handling 7prednylidene 6deltacortene 6Whole-Body Irradiation 6Methylprednisolone 6fludarabine phosphate 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
NETWORK × Precursor Cell Lymphoblastic Leukemia-Lymphoma × Drug Therapy × Clear all
NCT00458744 2014-08-08

Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment

Children's Oncology Group

Phase 1 Withdrawn
CNSLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Astrocytoma, Burkitt Lymphoma, Leukemia, Lymphoma, Medulloblastoma, Recurrence, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell, Leukemia, Myelomonocytic, Juvenile, Dendritic Cell Sarcoma, Interdigitating

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