Announcements Trials
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Phase

Phase 1 3

Status

Completed 3Terminated 1

Sponsor Class

NIH 2NETWORK 1

Study Type

Interventional 3

Sponsor

Cancer Type

Other hematologic neoplasm 3Lymphoid 3

Conditions

Glioblastoma 203Brain Neoplasms 94Gliosarcoma 93Glioma 88Central Nervous System Neoplasms 78Astrocytoma 66Oligodendroglioma 45Melanoma 37Medulloblastoma 18Neuroblastoma 17Neoplasm Metastasis 14Ependymoma 13Neoplasms 10Choroid Plexus Neoplasms 10Sarcoma 9Recurrence 9Optic Nerve Glioma 9Familial ependymoma 9Carcinoma, Non-Small-Cell Lung 9Ovarian Neoplasms 8Lung Neoplasms 8Spinal Cord Neoplasms 7Breast Neoplasms 7Uveal Melanoma 6Sarcoma, Ewing 6Rhabdoid Tumor 6Pinealoma 6Neuroectodermal Tumors, Primitive 6Unspecified Adult Solid Tumor, Protocol Specific 5Small Cell Lung Carcinoma 5

Interventions

Cyclophosphamide 216Methotrexate 140Cytarabine 131Vincristine 110fludarabine phosphate 103Peripheral Blood Stem Cell Transplantation 98Filgrastim 92Etoposide 92Dexamethasone 89Mycophenolic Acid 71Doxorubicin 70Whole-Body Irradiation 67Mercaptopurine 66Busulfan 65Tacrolimus 64Radiotherapy 63Cyclosporine 62Prednisone 55Daunorubicin 53pegaspargase 51Asparaginase 51Rituximab 48fludarabine 47Granulocyte Colony-Stimulating Factor 46Melphalan 45Antilymphocyte Serum 43Clofarabine 42Calcium Dobesilate 38Methylprednisolone 36Leucovorin 35

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Completed × Precursor Cell Lymphoblastic Leukemia-Lymphoma × Temozolomide × Clear all
NCT01139970 2025-11-20

Veliparib and Temozolomide in Treating Patients With Acute Leukemia

National Cancer Institute (NCI)

Phase 1 Completed
66 enrolled
LymphoidOther hematologic neoplasm

Burkitt Lymphoma, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Leukemia, Myelomonocytic, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT00083070 2014-02-20

Temozolomide in Treating Young Patients With Refractory or Recurrent Leukemia

Children's Oncology Group

Phase 1 Completed
16 enrolled
LymphoidOther hematologic neoplasm

Blast Crisis, Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00098436 2013-07-18

Temozolomide and VNP40101M in Treating Patients With Relapsed or Refractory Leukemias

National Cancer Institute (NCI)

Phase 1 Completed
25 enrolled
LymphoidOther hematologic neoplasm

Congenital Abnormalities, Blast Crisis, Leukemia, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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