Announcements Trials
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Phase

Phase EARLY_PHASE1 1Phase 1 1

Status

Recruiting 2Withdrawn 1Completed 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 2Lymphoid 2Plasma cell 1Classical hematology 1

Conditions

Multiple Myeloma 49Immunoglobulin Light-chain Amyloidosis 6Recurrence 5Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Neoplasms 3Neoplasm, Residual 3Lymphoma, Non-Hodgkin 3Leukemia, Myeloid, Acute 3Hematologic Neoplasms 3Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Plasmablastic Lymphoma 2Myelodysplastic Syndromes 2Lymphoma 2Smoldering Multiple Myeloma 1Proteostasis Deficiencies 1Primary Myelofibrosis 1Neoplasms, Plasma Cell 1Lymphoma, T-Cell, Peripheral 1Leukemia, Myelogenous, Chronic, BCR-ABL Positive 1Hodgkin Disease 1Carcinoma, Non-Small-Cell Lung 1Autoimmune Diseases of the Nervous System 1Anti-N-Methyl-D-Aspartate Receptor Encephalitis 1Anemia, Aplastic 1Amyloidosis 1Acute Kidney Injury 1

Interventions

Cyclophosphamide 55fludarabine 29Methotrexate 25blinatumomab 22Dexamethasone 22Cytarabine 21Vincristine 20venetoclax 18fludarabine phosphate 15Specimen Handling 15Whole-Body Irradiation 13Stem Cell Transplantation 11Biopsy 11Tacrolimus 10Prednisone 10Mycophenolic Acid 10Mercaptopurine 10Daunorubicin 10Thiotepa 9Rituximab 9Melphalan 9Immunotherapy, Adoptive 9Doxorubicin 8pegaspargase 7Magnetic Resonance Spectroscopy 7Inotuzumab Ozogamicin 7Granulocyte Colony-Stimulating Factor 7Cyclosporine 7Calcium Dobesilate 7ponatinib 6

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Recruiting × Precursor Cell Lymphoblastic Leukemia-Lymphoma × daratumumab × Clear all
NCT06287944 2026-05-18

225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

City of Hope Medical Center

Phase 1 Recruiting
15 enrolled
LymphoidMyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT06398457 2025-09-26

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase EARLY_PHASE1 Recruiting
8 enrolled
Classical hematologyLymphoidMyeloidOther hematologic neoplasmPlasma cell

Anemia, Aplastic, Hodgkin Disease, Lymphoma, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Primary Myelofibrosis

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