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Phase

Phase 1 1

Status

Recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Plasma cell 1Other hematologic neoplasm 1Myeloid 1Lymphoid 1

Conditions

Stomach Neoplasms 3Pancreatic Neoplasms 3Ovarian Neoplasms 3Carcinoma, Non-Small-Cell Lung 3Urogenital Neoplasms 2Triple Negative Breast Neoplasms 2Rectal Neoplasms 2Neoplasm Metastasis 2Multiple Myeloma 2Melanoma 2Gastrointestinal Neoplasms 2Colonic Neoplasms 2Carcinoma, Renal Cell 2Breast Neoplasms 2Urinary Bladder Neoplasms 1Thyroid Carcinoma, Anaplastic 1Squamous Cell Carcinoma of Head and Neck 1Sarcoma 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Osteosarcoma 1Neuroendocrine Tumors 1Myelodysplastic Syndromes 1Lung Neoplasms 1Leukemia, Myelomonocytic, Chronic 1Leukemia, Myeloid, Acute 1Leukemia, Myelogenous, Chronic, BCR-ABL Positive 1Histiocytoma, Malignant Fibrous 1Hematologic Neoplasms 1Giant Cell Tumor of Bone 1

Interventions

Cyclophosphamide 6Vincristine 4Methotrexate 4merphos 3fludarabine phosphate 3dexamethasone acetate 3dexamethasone 21-phosphate 3auricularum 3Specimen Handling 3Leucovorin 3Etoposide 3Doxorubicin 3Dexamethasone 3Cytarabine 3Calcium Dobesilate 3pegaspargase 2calaspargase pegol 2azathiopurine 2Whole-Body Irradiation 2Thioguanine 2Tacrolimus 2Sirolimus 2Peripheral Blood Stem Cell Transplantation 2Mercaptopurine 2Magnetic Resonance Spectroscopy 2Daunorubicin 2Asparaginase 2venetoclax 1revumenib 1prednylidene 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma × aldesleukin × 30 days × Clear all
NCT06904066 2026-06-15

Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies

National Institutes of Health Clinical Center (CC)

Phase 1 Recruiting
86 enrolled
LymphoidMyeloidOther hematologic neoplasmPlasma cell

Multiple Myeloma, Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

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