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Phase

Phase 3 1Phase 2/3 1Phase 1/2 1

Status

Withdrawn 1Not yet recruiting 1Active not recruiting 1

Sponsor Class

OTHER 19NIH 5NETWORK 3INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

Other hematologic neoplasm 3Lymphoid 3

Conditions

Leukemia 52Leukemia, Myeloid, Acute 30Precursor Cell Lymphoblastic Leukemia-Lymphoma 28Lymphoma 23Burkitt Lymphoma 16Leukemia, Monocytic, Acute 15Leukemia, Myelomonocytic, Acute 14Leukemia, Megakaryoblastic, Acute 14Leukemia, Erythroblastic, Acute 14Congenital Abnormalities 12Leukemia, Biphenotypic, Acute 9Myelodysplastic Syndromes 7Lymphoma, Large B-Cell, Diffuse 6Lymphoma, Non-Hodgkin 4Lymphoma, Mantle-Cell 4Leukemia, Eosinophilic, Acute 4Hodgkin Disease 4Dendritic Cell Sarcoma, Interdigitating 4Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 3Lymphoma, Large-Cell, Anaplastic 3Lymphoma, Follicular 3Leukemia, Basophilic, Acute 3Anemia, Refractory, with Excess of Blasts 3Waldenstrom Macroglobulinemia 2Recurrence 2Neutropenia 2Myeloproliferative Disorders 2Lymphoma, T-Cell 2Lymphoma, Large-Cell, Immunoblastic 2

Interventions

Vincristine 6Doxorubicin 5Cyclophosphamide 5merphos 4Specimen Handling 4Radiotherapy 4Prednisone 4Methotrexate 4pegaspargase 3calaspargase pegol 3Prednisolone 3Methylprednisolone 3Hydrocortisone 3Etoposide 3Daunorubicin 3Cytarabine 3Biopsy 3Asparaginase 3exifone 2dexamethasone acetate 2dexamethasone 21-phosphate 2daratumumab 2auricularum 2Thioguanine 2Spinal Puncture 2Mercaptopurine 2Medrol Veriderm 2Magnetic Resonance Spectroscopy 2Filgrastim 2Dexamethasone 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
NETWORK × Precursor T-Cell Lymphoblastic Leukemia-Lymphoma × Cytarabine × Clear all
NCT03007147 2026-05-04

Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Children's Oncology Group

Phase 3 Active not recruiting
475 enrolled
LymphoidOther hematologic neoplasm

Burkitt Lymphoma, Leukemia, Biphenotypic, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT07072585 2025-12-31

Testing the Addition of Daratumumab to Chemotherapy for Treating Patients With Newly-Diagnosed T-Cell Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LL)

Children's Oncology Group

Phase 2/3 Not yet recruiting
1,708 enrolled
LymphoidOther hematologic neoplasm

Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT05320380 2023-09-01

A Study of the Drug IMGN632 in Children With Leukemia That Has Come Back After Treatment or is Difficult to Treat

Children's Oncology Group

Phase 1/2 Withdrawn
LymphoidOther hematologic neoplasm

Burkitt Lymphoma, Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

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