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Phase

Phase 2 2Phase 1/2 2Phase 4 1Phase 1 1

Status

Recruiting 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Lymphoid 2

Conditions

Leukemia, Myeloid, Acute 62Myelodysplastic Syndromes 33Leukemia, Myelomonocytic, Chronic 16Leukemia 16Recurrence 9Lymphoma, Large B-Cell, Diffuse 6Leukemia, Myelomonocytic, Acute 5Leukemia, Myelogenous, Chronic, BCR-ABL Positive 5Leukemia, Monocytic, Acute 5Hodgkin Disease 5Myeloproliferative Disorders 4Congenital Abnormalities 4Anemia, Refractory, with Excess of Blasts 4Thrombocythemia, Essential 3Primary Myelofibrosis 3Polycythemia Vera 3Lymphoma 3Blast Crisis 3Triple Negative Breast Neoplasms 2Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Ovarian Neoplasms 2Neoplasm, Residual 2Leukemia, Myeloid, Accelerated Phase 2Leukemia, Megakaryoblastic, Acute 2Leukemia, Erythroblastic, Acute 2Carcinoma, Renal Cell 2Breast Neoplasms 2Thyroid Neoplasms 1Thyroid Cancer, Papillary 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1

Interventions

Cyclophosphamide 30fludarabine phosphate 19Peripheral Blood Stem Cell Transplantation 18Tacrolimus 17Mycophenolic Acid 16Methotrexate 16Whole-Body Irradiation 14Etoposide 13Vincristine 12Doxorubicin 12Dexamethasone 11Busulfan 11Cytarabine 10Antilymphocyte Serum 10venetoclax 9Prednisone 9nelarabine 8Rituximab 8Filgrastim 8Cyclosporine 8Calcium Dobesilate 8merphos 7Melphalan 7Radiotherapy 6prednylidene 5deltacortene 5Methylprednisolone 5Azacitidine 5Sirolimus 4Granulocyte Colony-Stimulating Factor 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 2 × Precursor T-Cell Lymphoblastic Leukemia-Lymphoma × Decitabine × Clear all
NCT06561074 2026-03-16

A Phase 2 Study to Evaluate Efficacy of Calaspargase Pegol-mknl and Decitabine Combined With Venetoclax in Pediatric, Adolescent, and Young Adult Patients With Relapsed/Refractory T-cell Acute Lymphoblastic Leukemia (T-ALL) and T- Cell Lymphoblastic Lymphoma (T-LLy)

M.D. Anderson Cancer Center

Phase 2 Recruiting
22 enrolled
LymphoidOther hematologic neoplasm

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT06686108 2025-05-07

Demethylating Agents Combined With Venetoclax for High-risk T-cell Lymphoblastic Lymphoma/Leukemia Post-Transplant Relapse Prevention

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Phase 2 Recruiting
59 enrolled
LymphoidOther hematologic neoplasm

Leukemia, Recurrence, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

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