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Phase

Phase 1 1

Status

Recruiting 2Withdrawn 1Unknown 1Terminated 1Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Plasma cell 1Other neoplasm 1Other hematologic neoplasm 1Myeloid 1Lymphoid 1

Conditions

Leukemia, Myeloid, Acute 79Myelodysplastic Syndromes 42Leukemia 23Leukemia, Myelomonocytic, Chronic 20Congenital Abnormalities 10Precursor Cell Lymphoblastic Leukemia-Lymphoma 8Recurrence 7Neoplasms 7Myeloproliferative Disorders 7Blast Crisis 7Leukemia, Myelogenous, Chronic, BCR-ABL Positive 6Leukemia, Myeloid, Accelerated Phase 5Carcinoma, Non-Small-Cell Lung 5Thrombocythemia, Essential 4Primary Myelofibrosis 4Polycythemia Vera 4Leukemia, Lymphocytic, Chronic, B-Cell 4Myelodysplastic-Myeloproliferative Diseases 3Lymphoma, Mantle-Cell 3Lymphoma, Large B-Cell, Diffuse 3Lung Neoplasms 3Leukemia, Myelomonocytic, Acute 3Leukemia, Monocytic, Acute 3Burkitt Lymphoma 3Anemia, Refractory, with Excess of Blasts 3Anemia, Refractory 3Small Cell Lung Carcinoma 2Neuroblastoma 2Neoplasm Metastasis 2Mesothelioma, Malignant 2

Interventions

Cyclophosphamide 25fludarabine phosphate 22Peripheral Blood Stem Cell Transplantation 22Whole-Body Irradiation 15Etoposide 13Cyclosporine 13Mycophenolic Acid 12Busulfan 12Tacrolimus 11Filgrastim 11Antilymphocyte Serum 11Methotrexate 9Prednisone 8Dexamethasone 8nelarabine 7Radiotherapy 7Doxorubicin 7Vincristine 6Methylprednisolone 6Calcium Dobesilate 6Vorinostat 5Paclitaxel 5Lenalidomide 5Everolimus 5Carboplatin 5Bortezomib 5merphos 4aldesleukin 4Therapeutics 4Rituximab 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Completed × Precursor T-Cell Lymphoblastic Leukemia-Lymphoma × Decitabine × Clear all
NCT00002980 2013-02-15

Decitabine in Treating Patients With Melanoma or Other Advanced Cancer

National Cancer Institute (NCI)

Phase 1 Completed
LymphoidMyeloidOther hematologic neoplasmOther neoplasmPlasma cell

Immunoglobulin Light-chain Amyloidosis, Blast Crisis, Burkitt Lymphoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Leukemia, Leukemia, Hairy Cell, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Monoclonal Gammopathy of Undetermined Significance, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Polycythemia Vera, Precancerous Conditions, Thrombocythemia, Essential, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Prolymphocytic, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Primary Myelofibrosis

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