Announcements Trials
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Phase

Phase 3 3Phase 2 2Phase 2/3 1

Status

Active not recruiting 2Completed 1

Sponsor Class

NIH 2NETWORK 1

Study Type

Interventional 3

Sponsor

Cancer Type

Other hematologic neoplasm 3Lymphoid 3

Conditions

Leukemia 20Precursor Cell Lymphoblastic Leukemia-Lymphoma 15Burkitt Lymphoma 8Leukemia, Myeloid, Acute 5Myelodysplastic Syndromes 4Lymphoma 4Leukemia, Myelomonocytic, Chronic 4Anemia, Refractory, with Excess of Blasts 4Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 3Myeloproliferative Disorders 3Leukemia, Biphenotypic, Acute 3Down Syndrome 3Myelodysplastic-Myeloproliferative Diseases 2Leukemia, Promyelocytic, Acute 2Leukemia, Myelomonocytic, Acute 2Leukemia, Monocytic, Acute 2Leukemia, Megakaryoblastic, Acute 2Leukemia, Erythroblastic, Acute 2Anemia, Refractory 2Optic Nerve Glioma 1Neutropenia 1Neoplasm Metastasis 1Leukemia, Myelomonocytic, Juvenile 1Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 1Leukemia, Eosinophilic, Acute 1Dendritic Cell Sarcoma, Interdigitating 1Congenital Abnormalities 1Central Nervous System Neoplasms 1Brain Neoplasms 1

Interventions

pegaspargase 4Vincristine 4Doxorubicin 4Cytarabine 4Cyclophosphamide 4merphos 3dexamethasone acetate 3dexamethasone 21-phosphate 3azathiopurine 3auricularum 3Thioguanine 3Radiotherapy 3Methotrexate 3Mercaptopurine 3Leucovorin 3Dexamethasone 3Daunorubicin 3Calcium Dobesilate 3Asparaginase 3nelarabine 2liposomal amphotericin B 2calaspargase pegol 2Radiation 2Prednisone 2Levofloxacin 2Ifosfamide 2Hydrocortisone 2Granulocyte Colony-Stimulating Factor 2Filgrastim 2Etoposide 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 3 × Precursor T-Cell Lymphoblastic Leukemia-Lymphoma × Thioguanine × Clear all
NCT02112916 2026-06-03

Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma

National Cancer Institute (NCI)

Phase 3 Active not recruiting
847 enrolled 19 charts
LymphoidOther hematologic neoplasm

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT03007147 2026-05-04

Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Children's Oncology Group

Phase 3 Active not recruiting
475 enrolled
LymphoidOther hematologic neoplasm

Burkitt Lymphoma, Leukemia, Biphenotypic, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT00408005 2025-04-20

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma

National Cancer Institute (NCI)

Phase 3 Completed
1,895 enrolled 16 charts
LymphoidOther hematologic neoplasm

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

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