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Phase

Phase 2 7Phase 1/2 4Phase 3 3Phase 2/3 1

Status

Active not recruiting 2Completed 1

Sponsor Class

NIH 2NETWORK 1

Study Type

Interventional 3

Sponsor

Cancer Type

Other hematologic neoplasm 3Lymphoid 3

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 12Burkitt Lymphoma 8Leukemia, Biphenotypic, Acute 5Leukemia, Myeloid, Acute 4Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 3Myeloproliferative Disorders 2Myelodysplastic Syndromes 2Hydatidiform Mole 2Down Syndrome 2Urinary Bladder Neoplasms 1Rhabdoid Tumor 1Osteosarcoma 1Myeloproliferative Syndrome, Transient 1Multiple Myeloma 1Medulloblastoma 1Lymphoma, Non-Hodgkin 1Leukemia, Promyelocytic, Acute 1Leukemia, Myelomonocytic, Chronic 1Leukemia, Myelogenous, Chronic, BCR-ABL Positive 1Leukemia, Lymphocytic, Chronic, B-Cell 1Hodgkin Disease 1Graft vs Host Disease 1Congenital Abnormalities 1Chromosome 5q Deletion Syndrome 1Choriocarcinoma 1Childhood Acute Promyelocytic Leukemia With PML-RARA 1Anemia, Refractory, with Excess of Blasts 1Anemia, Refractory 1

Interventions

pegaspargase 4Vincristine 4Doxorubicin 4Cytarabine 4Cyclophosphamide 4merphos 3dexamethasone acetate 3dexamethasone 21-phosphate 3azathiopurine 3auricularum 3Thioguanine 3Radiotherapy 3Methotrexate 3Mercaptopurine 3Leucovorin 3Dexamethasone 3Daunorubicin 3Calcium Dobesilate 3Asparaginase 3nelarabine 2liposomal amphotericin B 2calaspargase pegol 2Radiation 2Prednisone 2Levofloxacin 2Ifosfamide 2Hydrocortisone 2Granulocyte Colony-Stimulating Factor 2Filgrastim 2Etoposide 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 3 × Precursor T-Cell Lymphoblastic Leukemia-Lymphoma × merphos × Clear all
NCT02112916 2026-05-27

Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma

National Cancer Institute (NCI)

Phase 3 Active not recruiting
847 enrolled 19 charts
LymphoidOther hematologic neoplasm

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT03007147 2026-05-04

Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Children's Oncology Group

Phase 3 Active not recruiting
475 enrolled
LymphoidOther hematologic neoplasm

Burkitt Lymphoma, Leukemia, Biphenotypic, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT00408005 2025-04-20

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma

National Cancer Institute (NCI)

Phase 3 Completed
1,895 enrolled 16 charts
LymphoidOther hematologic neoplasm

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

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