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Phase

Phase 1/2 1Phase 1 1

Status

Recruiting 10Withdrawn 2Not yet recruiting 2Active not recruiting 2Terminated 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Lymphoid 2

Conditions

Leukemia, Myeloid, Acute 26Leukemia, Lymphocytic, Chronic, B-Cell 6Leukemia 4Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Leukemia, Myeloid 2Renal Insufficiency, Chronic 1Recurrence 1Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 1Pathologic Complete Response 1Older Patients 1Neoplasm, Residual 1Myelodysplastic Syndromes 1Lymphoma, Mantle-Cell 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, B-Cell 1Lymphoma 1Leukemia, Prolymphocytic, T-Cell 1Hematologic Neoplasms 1Blastic Plasmacytoid Dendritic Cell Neoplasm 1

Interventions

venetoclax 2daratumumab 2Dexamethasone 2Bortezomib 2prednylidene 1pegaspargase 1nelarabine 1merphos 1exifone 1dexamethasone acetate 1dexamethasone 21-phosphate 1deltacortene 1capivasertib 1calaspargase pegol 1auricularum 1Vincristine 1Thioguanine 1Spinal Puncture 1Specimen Handling 1Radiotherapy 1Radiation 1Prednisone 1Prednisolone 1Methylprednisolone 1Methotrexate 1Mercaptopurine 1Medrol Veriderm 1Magnetic Resonance Spectroscopy 1Hydrocortisone 1High-Energy Shock Waves 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Not yet recruiting × Precursor T-Cell Lymphoblastic Leukemia-Lymphoma × venetoclax × Clear all
NCT07513129 2026-04-21

Venetoclax, Dexamethasone, Bortezomib, and Daratumumab For The Treatment Of Adolescent And Young Adults With Relapsed Or Refractory T-Cell Acute Lymphoblastic Leukemia And T-cell Acute Lymphoblastic Lymphoma

M.D. Anderson Cancer Center

Phase 1 Not yet recruiting
18 enrolled
LymphoidOther hematologic neoplasm

Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT07175415 2025-09-16

HEM-iSMART E

Princess Maxima Center for Pediatric Oncology

Phase 1/2 Not yet recruiting
42 enrolled
LymphoidOther hematologic neoplasm

Leukemia, Recurrence, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

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