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Phase

Phase EARLY_PHASE1 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Conditions

Lymphoma 6Pancreatic Neoplasms 5Prostatic Neoplasms 4Neoplasms 4Glioma 4Sarcoma 3Neoplasm Metastasis 3Melanoma 3Colorectal Neoplasms 3Breast Neoplasms 3Squamous Cell Carcinoma of Head and Neck 2Recurrence 2Pancreatic Ductal Adenocarcinoma 2Myelodysplastic Syndromes 2Multiple Myeloma 2Leukemia, Lymphocytic, Chronic, B-Cell 2Leukemia 2Immunoglobulin Light-chain Amyloidosis 2Head and Neck Neoplasms 2Carcinoma, Transitional Cell 2Carcinoma, Squamous Cell 2Carcinoma, Basal Cell 2Burkitt Lymphoma 2Advanced Solid Tumors 2Uterine Cervical Neoplasms 1Triple Negative Breast Neoplasms 1Stomach Neoplasms 1Smoking Cessation 1Skin Neoplasms 1Sarcoma, Ewing 1

Interventions

mirdametinib 1Vorinostat 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Phase EARLY_PHASE1 × Primary Malignant Peripheral Nerve Sheath Tumors × 30 days × Clear all
NCT06693284 2026-05-29

A Window of Opportunity Trial of Mirdametinib Plus Vorinostat for NF1 Associated, H3K27 Trimethylation Deficient Malignant Peripheral Nerve Sheath Tumor [MPNST]

University of Minnesota

Phase EARLY_PHASE1 Recruiting
8 enrolled

Primary Malignant Peripheral Nerve Sheath Tumors

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