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Phase

Phase EARLY_PHASE1 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Conditions

Breast Neoplasms 251Neoplasms 175Prostatic Neoplasms 146Colorectal Neoplasms 108Lung Neoplasms 99Leukemia, Myeloid, Acute 77Pancreatic Neoplasms 76Carcinoma, Non-Small-Cell Lung 69Multiple Myeloma 67Brain Neoplasms 65Melanoma 55Precursor Cell Lymphoblastic Leukemia-Lymphoma 54Ovarian Neoplasms 53Glioblastoma 50Head and Neck Neoplasms 49Uterine Cervical Neoplasms 48Neoplasm Metastasis 48Carcinoma, Hepatocellular 48Recurrence 41Sarcoma 39Hematologic Neoplasms 39Glioma 39Endometrial Neoplasms 37Carcinoma, Renal Cell 37Squamous Cell Carcinoma of Head and Neck 36Lymphoma, Non-Hodgkin 36Stomach Neoplasms 35Rectal Neoplasms 35Lymphoma 34Leukemia 34

Interventions

mirdametinib 1Vorinostat 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
OTHER × Primary Malignant Peripheral Nerve Sheath Tumors × 30 days × Clear all
NCT06693284 2026-05-29

A Window of Opportunity Trial of Mirdametinib Plus Vorinostat for NF1 Associated, H3K27 Trimethylation Deficient Malignant Peripheral Nerve Sheath Tumor [MPNST]

University of Minnesota

Phase EARLY_PHASE1 Recruiting
8 enrolled

Primary Malignant Peripheral Nerve Sheath Tumors

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