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Phase

Phase EARLY_PHASE1 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

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Conditions

Breast Neoplasms 9485Neoplasms 6599Prostatic Neoplasms 4404Colorectal Neoplasms 3979Lung Neoplasms 3647Carcinoma, Non-Small-Cell Lung 3587Pancreatic Neoplasms 2480Carcinoma, Hepatocellular 2416Leukemia, Myeloid, Acute 2266Multiple Myeloma 2123Stomach Neoplasms 2109Neoplasm Metastasis 1913Head and Neck Neoplasms 1873Ovarian Neoplasms 1778Precursor Cell Lymphoblastic Leukemia-Lymphoma 1734Lymphoma 1731Brain Neoplasms 1706Rectal Neoplasms 1676Melanoma 1657Colonic Neoplasms 1629Uterine Cervical Neoplasms 1501Leukemia 1500Recurrence 1486Esophageal Neoplasms 1312Glioblastoma 1310Lymphoma, Non-Hodgkin 1205Leukemia, Lymphocytic, Chronic, B-Cell 1120Squamous Cell Carcinoma of Head and Neck 1109Urinary Bladder Neoplasms 1080Lymphoma, Follicular 1069

Interventions

mirdametinib 1Vorinostat 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
OTHER × Primary Malignant Peripheral Nerve Sheath Tumors × Clear all
NCT06693284 2026-05-29

A Window of Opportunity Trial of Mirdametinib Plus Vorinostat for NF1 Associated, H3K27 Trimethylation Deficient Malignant Peripheral Nerve Sheath Tumor [MPNST]

University of Minnesota

Phase EARLY_PHASE1 Recruiting
8 enrolled

Primary Malignant Peripheral Nerve Sheath Tumors

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