Announcements Trials
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Phase

Phase 3 1Phase 2 1

Status

Completed 1Active not recruiting 1

Sponsor Class

INDUSTRY 2

Study Type

Interventional 2

Sponsor

Cancer Type

Myeloid 2

Conditions

Myelodysplastic Syndromes 3Primary Myelofibrosis 2Myeloproliferative Disorders 2Leukemia, Myeloid, Acute 2Breast Neoplasms 2Thrombocytosis 1Rhabdomyosarcoma 1Recurrence 1Polycythemia 1Osteosarcoma 1Oligodendroglioma 1Neuroectodermal Tumors, Primitive, Peripheral 1Neuroblastoma 1Neoplasms, Plasma Cell 1Multiple Myeloma 1Leukemia, Prolymphocytic, T-Cell 1Leukemia, Myelomonocytic, Juvenile 1Leukemia, Lymphocytic, Chronic, B-Cell 1Hepatoblastoma 1Gliosarcoma 1Glioblastoma 1Ependymoma 1Carcinoma, Non-Small-Cell Lung 1Brain Stem Neoplasms 1Astrocytoma 1

Interventions

Cyclophosphamide 62fludarabine phosphate 55Peripheral Blood Stem Cell Transplantation 44Tacrolimus 41Busulfan 40ruxolitinib 39Mycophenolic Acid 36Whole-Body Irradiation 32Antilymphocyte Serum 29Methotrexate 27Cyclosporine 27fludarabine 24Melphalan 19Filgrastim 19Radiotherapy 15Methylprednisolone 13thymoglobulin 12Etoposide 12Cord Blood Stem Cell Transplantation 12Azacitidine 12Stem Cell Transplantation 11Sirolimus 1111-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,26-triazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene 10Decitabine 9Specimen Handling 8Prednisone 8Cytarabine 8Imatinib Mesylate 7Granulocyte Colony-Stimulating Factor 7Flow Cytometry 7

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Interventional × Primary Myelofibrosis × GRN163L peptide × Clear all
NCT04576156 2025-12-04

A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment

Geron Corporation

Phase 3 Active not recruiting
327 enrolled
Myeloid

Myeloproliferative Disorders, Polycythemia, Thrombocytosis, Primary Myelofibrosis

NCT01731951 2021-09-21

Imetelstat Sodium in Treating Participants With Primary or Secondary Myelofibrosis

Geron Corporation

Phase 2 Completed
80 enrolled 31 charts
Myeloid

Myelodysplastic Syndromes, Myeloproliferative Disorders, Primary Myelofibrosis

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