Announcements Trials
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Phase

Phase 1/2 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1

Conditions

Breast Neoplasms 3Leukemia, Myelomonocytic, Chronic 2Triple Negative Breast Neoplasms 1Primary Myelofibrosis 1Neoplasm Metastasis 1Myeloproliferative Disorders 1Myelodysplastic-Myeloproliferative Diseases 1Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 1

Interventions

ruxolitinib 6Specimen Handling 6Stem Cell Transplantation 5Cyclophosphamide 4fludarabine 3Mycophenolic Acid 3Biopsy 311-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,26-triazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene 3Whole-Body Irradiation 2Tacrolimus 2Sirolimus 2Methotrexate 2Melphalan 2Hematopoietic Stem Cell Transplantation 2Blood Component Removal 2thymoglobulin 1talazoparib 1tagraxofusp 1reparixin 1poly ICLC 1piperine 1pegylated granulocyte colony-stimulating factor 1merphos 1letermovir 1fludarabine phosphate 1fedratinib 1demethoxycurcumin 1daratumumab 1bomedemstat 1axatilimab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Recruiting × Primary Myelofibrosis × axatilimab × Clear all
NCT07128381 2026-01-05

Phase I/II Clinical Trial of Axatilimab, a CSF1R Monoclonal Antibody, in Combination With Ruxolitinib as Therapy for Patients With Myelofibrosis (MF) and Chronic Myelomonocytic Leukemia (CMML)

M.D. Anderson Cancer Center

Phase 1/2 Recruiting
66 enrolled
MyeloidOther hematologic neoplasm

Leukemia, Myelomonocytic, Chronic, Primary Myelofibrosis

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