Announcements Trials
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Phase

Phase 2 4

Status

Completed 3Active not recruiting 1

Sponsor Class

INDUSTRY 3OTHER 1

Study Type

Interventional 4

Sponsor

Cancer Type

Myeloid 4Other hematologic neoplasm 1Lymphoid 1

Conditions

Myeloproliferative Disorders 5Primary Myelofibrosis 4Carcinoma, Non-Small-Cell Lung 4Hematologic Neoplasms 3Thrombocytosis 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Polycythemia Vera 1Myelodysplastic Syndromes 1Lymphoma, Non-Hodgkin 1Lymphoma, Large B-Cell, Diffuse 1Leukemia, Myelomonocytic, Chronic 1Leukemia, Myeloid, Acute 1Hodgkin Disease 1Hematologic Diseases 1Gastrointestinal Neoplasms 1Breast Neoplasms 1

Interventions

Cyclophosphamide 36fludarabine phosphate 32Tacrolimus 28Busulfan 24Peripheral Blood Stem Cell Transplantation 23Mycophenolic Acid 20Whole-Body Irradiation 19Antilymphocyte Serum 18Methotrexate 16fludarabine 14ruxolitinib 13Melphalan 12Cyclosporine 12thymoglobulin 8Stem Cell Transplantation 8Radiotherapy 8Methylprednisolone 8Sirolimus 6Prednisone 6Cord Blood Stem Cell Transplantation 6Specimen Handling 5Filgrastim 5Etoposide 5Alemtuzumab 5merphos 4itacitinib 4Imatinib Mesylate 4INCB039110 4Hematopoietic Stem Cell Transplantation 4Cytarabine 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Phase 2 × Primary Myelofibrosis × itacitinib × Clear all
NCT05364762 2026-06-03

Adding Itacitinib to Cyclophosphamide and Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Hematopoietic Stem Cell Transplants

City of Hope Medical Center

Phase 2 Active not recruiting
20 enrolled
LymphoidMyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Primary Myelofibrosis

NCT04629508 2025-09-02

To Assess the Safety, Tolerability and Efficacy of Itacitinib Immediate Release Tablets in Participants With Primary or Secondary Myelofibrosis Who Have Received Prior Ruxolitinib and/or Fedratinib Monotherapy (LIMBER-213)

Incyte Corporation

Phase 2 Completed
4 enrolled 10 charts
Myeloid

Myeloproliferative Disorders, Polycythemia Vera, Thrombocytosis, Primary Myelofibrosis

NCT03144687 2022-06-16

A Study of Itacitinib in Combination With Low-Dose Ruxolitinib or Itacitinib Alone Following Ruxolitinib in Participants With Myelofibrosis

Incyte Corporation

Phase 2 Completed
23 enrolled 31 charts
Myeloid

Myeloproliferative Disorders, Primary Myelofibrosis

NCT01633372 2021-08-30

An Open Label Study of Itacitinib Administered Orally in Patients With Myelofibrosis

Incyte Corporation

Phase 2 Completed
87 enrolled
Myeloid

Myeloproliferative Disorders, Primary Myelofibrosis

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