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Phase

Phase 2 1Phase 1/2 1

Status

Completed 84Terminated 25Recruiting 13Active not recruiting 11Withdrawn 5Unknown 2Suspended 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Myeloid 1

Conditions

Colorectal Neoplasms 6Stomach Neoplasms 5Melanoma 5Carcinoma, Non-Small-Cell Lung 5Prostatic Neoplasms 4Neoplasm Metastasis 4Leukemia, Myeloid, Acute 4Glioblastoma 4Breast Neoplasms 4Pancreatic Neoplasms 3Neoplasms 3Myelodysplastic Syndromes 3Glioma 3Carcinoma, Renal Cell 3Uterine Cervical Neoplasms 2Sarcoma 2Rectal Neoplasms 2Peritoneal Neoplasms 2Osteosarcoma 2Nasopharyngeal Carcinoma 2Multiple Myeloma 2Mesothelioma, Malignant 2Lymphoma 2Lung Neoplasms 2Leukemia, Lymphocytic, Chronic, B-Cell 2Diffuse Intrinsic Pontine Glioma 2Warts 1Urinary Bladder Neoplasms 1Thyroid Neoplasms 1Thrombocythemia, Essential 1

Interventions

iadademstat 1decitabine and cedazuridine drug combination 1Specimen Handling 1Biopsy 1

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 2 × Suspended × Primary Myelofibrosis × Clear all
NCT06661915 2026-05-29

A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)

National Cancer Institute (NCI)

Phase 2 Suspended
62 enrolled
Myeloid

Myeloproliferative Disorders, Polycythemia Vera, Thrombocythemia, Essential, Myelodysplastic-Myeloproliferative Diseases, Primary Myelofibrosis

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