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Phase

Phase 2 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Genitourinary 1

Conditions

Prostatic Neoplasms 7Squamous Cell Carcinoma of Head and Neck 4Carcinoma, Non-Small-Cell Lung 4Sarcoma, Ewing 2Rhabdomyosarcoma 2Oropharyngeal Neoplasms 2Breast Neoplasms 2Adenocarcinoma 2Wilms Tumor 1Triple Negative Breast Neoplasms 1Stomatitis 1Stage III Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v6 and v7 1Squamous Cell Cancer of Head and Neck (SCCHN) 1Sarcoma, Clear Cell 1Sarcoma 1Rhabdoid Tumor 1Recurrence 1Prostate Cancer Metastatic 1Prostate Adenocarcinoma 1Pelvic Neoplasms 1Osteosarcoma 1Neuroectodermal Tumors, Primitive 1Neuroblastoma 1Neoplasms, Germ Cell and Embryonal 1Neoplasm Metastasis 1Nasopharyngeal Carcinoma 1Mouth Neoplasms 1Meningioma 1Medulloblastoma 1Malignant Liver Neoplasm 1

Interventions

Radiotherapy 3Radiation 3Magnetic Resonance Spectroscopy 3relugolix 2luprolide acetate gel depot 2enzalutamide 2bicalutamide 2acetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ILys-prolyl-alaninamide 2Specimen Handling 2Radiosurgery 2Leuprolide 2Goserelin 2Biopsy 2radium Ra 223 dichloride 1niraparib 1histrelin 1gallium 68 PSMA-11 1darolutamide 1abiraterone 1X-Rays 1Triptorelin Pamoate 1Surgical Procedures, Operative 1Salicylic Acid 1Radium-223 1Radiotherapy, Image-Guided 1Radiation Dose Hypofractionation 1Proton Therapy 1Prednisone 1Lymph Node Excision 1Glutamate Carboxypeptidase II 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Prostate Adenocarcinoma × Radiotherapy, Image-Guided × 1 year × Clear all
NCT06499870 2026-06-05

Relugolix and Enzalutamide in Combination With Radiation Therapy for the Treatment of Very High Risk Prostate Cancer, OPTIMAL Trial

Northwestern University

Phase 2 Recruiting
50 enrolled
Genitourinary

Prostate Adenocarcinoma

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