Clinical Trials Browser

Phase 1 × INDUSTRY × Prostatic Neoplasms, Castration-Resistant × Clear all

NCT02592317 2026-05-08

A Study to Evaluate the Effect of Multiple Doses of JNJ-56021927 on the Pharmacokinetics of Multiple Cytochrome P450 and Transporter Substrates in Participants With Castration-Resistant Prostate Cancer

Phase 1 Active not recruiting

23 enrolled

Genitourinary

Prostatic Neoplasms, Castration-Resistant

NCT06788509 2026-05-08

A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring

Phase 1 Enrolling by invitation

120 enrolled

GenitourinaryLymphoidMyeloidOther hematologic neoplasm

Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Acute, Prostatic Neoplasms, Castration-Resistant

NCT04597411 2026-04-30

Study of 225Ac-PSMA-617 in Men With PSMA-positive Prostate Cancer

Phase 1 Active not recruiting

101 enrolled

Genitourinary

Genital Diseases, Male, Genital Neoplasms, Male, Neoplasms, Neoplasms by Site, Prostatic Diseases, Prostatic Neoplasms, Urogenital Neoplasms, Prostatic Neoplasms, Castration-Resistant

NCT05997615 2026-04-20

AMX-500

Phase 1 Recruiting

390 enrolled

Genitourinary

Prostatic Neoplasms, Prostatic Neoplasms, Castration-Resistant

NCT06242470 2026-02-05

A Study of MGC026 in Participants With Advanced Solid Tumors

Phase 1 Recruiting

250 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Small Cell Lung Carcinoma, Prostatic Neoplasms, Castration-Resistant

NCT06067841 2026-02-04

A Study to Assess BMS-986460 in Participants With Metastatic Castration-resistant Prostate Cancer

Phase 1 Recruiting

140 enrolled

Genitourinary

Neoplasms, Prostatic Neoplasms, Prostatic Neoplasms, Castration-Resistant

NCT05519449 2026-01-20

ENGAGER-PSMA-01

Phase 1 Recruiting

272 enrolled

Genitourinary

Prostatic Neoplasms, Prostatic Neoplasms, Castration-Resistant

NCT04428788 2025-12-22

Study to Evaluate the Safety and Tolerability of CC-94676 in Participants With Metastatic Castration-Resistant Prostate Cancer

Phase 1 Completed

131 enrolled

Genitourinary

Neoplasms, Prostatic Neoplasms, Prostatic Neoplasms, Castration-Resistant

NCT05252390 2025-11-06

NUV-868 as Monotherapy and in Combination With Olaparib or Enzalutamide in Adult Patients With Advanced Solid Tumors

Phase 1 Terminated

82 enrolled

BreastGastrointestinalGenitourinaryGynecologic

Breast Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Prostatic Neoplasms, Castration-Resistant, Triple Negative Breast Neoplasms

NCT05293496 2025-10-14

A Study of MGC018 in Combination With MGD019 in Participants With Advanced Solid Tumors

Phase 1 Completed

31 enrolled

DermatologicGastrointestinalGenitourinaryGynecologic

Carcinoma, Ovarian Epithelial, Carcinoma, Renal Cell, Liver Neoplasms, Melanoma, Carcinoma, Pancreatic Ductal, Prostatic Neoplasms, Castration-Resistant

NCT02204072 2025-07-15

BI836845 Plus Enzalutamide in Castrate Resistant Prostate Cancer (CRPC)

Phase 1 Completed

120 enrolled 28 charts

Genitourinary

Prostatic Neoplasms, Castration-Resistant

NCT04249947 2025-02-17

P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)

Phase 1 Terminated

40 enrolled

GenitourinaryHead & Neck

Carcinoma, Adenoid Cystic, Genital Neoplasms, Male, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Prostatic Diseases, Prostatic Neoplasms, Salivary Gland Neoplasms, Urogenital Neoplasms, Carcinoma, Acinar Cell, Carcinoma, Mucoepidermoid, Prostatic Neoplasms, Castration-Resistant

NCT02625857 2025-02-03