Clinical Trials

64 enrolled

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT02465060 2026-06-03

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther hematologic neoplasmPlasma cellThoracic

6,452 enrolled 1 FDA

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Glioma, Carcinoma, Hepatocellular, Lung Neoplasms, Lymphoma, Melanoma, Multiple Myeloma, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms, Thyroid Neoplasms, Uterine Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Hematologic Neoplasms

NCT05308446 2026-06-03

Testing the Addition of Nivolumab to Standard Treatment for Patients With Metastatic or Unresectable Colorectal Cancer That Have a BRAF Mutation

86 enrolled

Colonic Neoplasms, Rectal Neoplasms

NCT05007015 2026-06-02

TAI-LARS

66 enrolled

Low Anterior Resection Syndrome, Rectal Neoplasms

NCT05056077 2026-06-02

TTBF

BreastGastrointestinalGenitourinaryGynecologic

353 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Renal Cell, Colonic Neoplasms, Kidney Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Endometrial Neoplasms

NCT04751370 2026-05-29

Testing Nivolumab and Ipilimumab With Short-Course Radiation in Locally Advanced Rectal Cancer

31 enrolled

Phase 1 Active not recruiting

Rectal Neoplasms

NCT02403505 2026-05-28

CEA+RC-BCG

20 enrolled

Rectal Neoplasms

NCT05723562 2026-05-26

AZUR-1

154 enrolled

Rectal Neoplasms

NCT06337552 2026-05-26

High-Fermented Food Intervention Among Locally Advanced Rectal Cancer Patients (The FEED Trial)

Phase 1 Active not recruiting

39 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Rectal Neoplasms

NCT06607185 2026-05-26

A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

750 enrolled

GastrointestinalGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT03548961 2026-05-22

Organ Preservation in Early Rectal Cancer Patients

19 enrolled

Phase 1/2 Active not recruiting

Rectal Neoplasms

NCT04017650 2026-05-22

Encorafenib, Cetuximab, and Nivolumab in Treating Patients With Microsatellite Stable, BRAFV600E Mutated Unresectable or Metastatic Colorectal Cancer

38 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Disease Progression

NCT04503694 2026-05-22

REGINA

72 enrolled

Phase 1/2 Active not recruiting

Rectal Neoplasms

NCT05726864 2026-05-19

AMPLIFY-7P

158 enrolled

Phase 1/2 Active not recruiting

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT04432597 2026-05-18

HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers

39 enrolled

GastrointestinalGynecologicHead & Neck

Anus Neoplasms, Uterine Cervical Neoplasms, Oropharyngeal Neoplasms, Rectal Neoplasms

NCT06904365 2026-05-18

OvAR-Y

Active not recruiting

10 enrolled

BreastGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

Anus Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Rectal Neoplasms, Sarcoma, Stomach Neoplasms, Uterine Neoplasms

NCT03516942 2026-05-15

Financial Burden Assessment in Patients With Stage I-III Colon or Rectal Cancer Undergoing Treatment

Active not recruiting

565 enrolled 16 charts

Phase 1 Active not recruiting

Colonic Neoplasms, Rectal Neoplasms

NCT05462717 2026-05-15

Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors

222 enrolled

GastrointestinalGynecologicThoracic

Appendiceal Neoplasms, Bronchial Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Intestinal Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms by Site, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Stomach Neoplasms, Thoracic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Carcinoma, Pancreatic Ductal

NCT04929028 2026-05-13

Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer

40 enrolled

GastrointestinalGynecologic

Anus Neoplasms, Rectal Neoplasms, HIV Infections

NCT04713618 2026-05-07

GEORGIA

Active not recruiting

72 enrolled

Anus Neoplasms, Uterine Cervical Neoplasms, Pelvic Neoplasms, Rectal Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Endometrial Neoplasms

NCT01558921 2026-05-01

RAPIDO

Phase 3 Active not recruiting

920 enrolled 17 charts

Rectal Neoplasms

NCT01696981 2026-04-30

Screening for Colorectal Cancer in Older Patients (PLCO Screening Trial)

154,900 enrolled 15 charts

Colonic Neoplasms, Rectal Neoplasms

NCT04084249 2026-04-29

ctDNA-guided Surveillance for Stage III CRC, a Randomized Intervention Trial

359 enrolled