Clinical Trials Browser

Rectal Neoplasms × Chemoradiotherapy × Clear all

NCT06758830 2026-05-11

Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer.

Phase 2/3 Recruiting

Gastrointestinal

Low Anterior Resection Syndrome, Fatigue, Postoperative Complications, Radiation Injuries, Rectal Neoplasms

NCT06647680 2026-03-06

Neoadjuvant Chemotherapy and PD-1 Inhibitor for Locally Advanced Rectal Cancer（CONTROL-01）

Phase 2 Recruiting

Gastrointestinal

Pathologic Complete Response, Rectal Neoplasms

NCT04215731 2026-03-03

FOBEAR

Phase 3 Recruiting

Gastrointestinal

Rectal Neoplasms

NCT03051464 2026-02-17

Morpheus

Phase 2/3 Recruiting

Gastrointestinal

Rectal Neoplasms

NCT05673772 2026-02-12

SOLAR

Phase 2 Active not recruiting

Gastrointestinal

Rectal Neoplasms

NCT03875781 2026-01-15

NORAD01

Phase 3 Recruiting

Gastrointestinal

Rectal Neoplasms

NCT05358704 2025-12-04

Preoperative ChemoRadiation And FOLFOXIRI for Rectal Cancer (CRAFTER) for Rectal Cancer

Phase 2 Suspended

Gastrointestinal

Rectal Neoplasms

NCT03879109 2024-08-14

GRECCAR15

Phase 3 Active not recruiting

Gastrointestinal

Rectal Neoplasms

NCT04124601 2024-04-23

CHINOREC

Phase 2 Completed

Gastrointestinal

Rectal Neoplasms

NCT04543695 2024-03-26

A Study of Total Neoadjuvant Therapy for High-risk Locally Advanced Rectal Cancer

Phase 2 Unknown

Gastrointestinal

Rectal Neoplasms

NCT06300489 2024-03-08

Genotype-driven Weekly Irinotecan Liposomes in Combination With Capecitabine-based Neoadjuvant Chemoradiation for Locally Advanced Rectal Cancer

Phase 1 Unknown

Gastrointestinal

Rectal Neoplasms

NCT01515787 2024-02-02

PROSPECT: Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing Surgery

Phase 2/3 Unknown

1,194 enrolled 25 charts

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT06239870 2024-02-02

ESTIMATE

Phase 2 Unknown

Gastrointestinal

Rectal Neoplasms

NCT05450029 2023-09-26

SILAR

Phase 2 Recruiting

Gastrointestinal

Rectal Neoplasms

NCT02031939 2023-08-25

Randomized Controlled Study on Optimize Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer

Phase 3 Unknown

Gastrointestinal

Rectal Neoplasms

NCT04389086 2022-09-06

PelvEx II

Phase 3 Recruiting

Gastrointestinal

Margins of Excision, Rectal Neoplasms

NCT05339763 2022-04-21

Long Term Bowel Function Following Rectal Cancer Surgery

Phase NA Completed

Gastrointestinal

Rectal Neoplasms, Irritable Bowel Syndrome

NCT04418895 2021-11-10

Neoadjuvant Therapy for Localized Rectal Adenocarcinoma

Phase 2 Withdrawn

Gastrointestinal

Rectal Neoplasms

NCT02948348 2021-09-16

Study to Nivolumab Following Preoperative Chemoradiotherapy

Phase 1/2 Unknown

Gastrointestinal

Rectal Neoplasms

NCT04747951 2021-02-15

Total Neoadjuvant Therapy in Rectal Cancer Treatment

Phase 4 Unknown

Gastrointestinal

Rectal Neoplasms

NCT01224392 2020-12-30

RectumSIB

Phase 3 Completed

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT02233595 2019-08-13

Rectal PET/MRI

Gastrointestinal

Rectal Neoplasms

NCT03975049 2019-06-05

Triplet Combination or Doublet Regimen Versus Chemoradiation as Neoadjuvant Therapy for Locally Advanced Rectal Cancer

Phase 3 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT01863862 2019-03-29

Organ Preservation in Elderly Patients With Rectal Cancer

Phase NA Unknown

Gastrointestinal

Pathologic Complete Response, Rectal Neoplasms

NCT03671252 2019-01-23

Prospectively Randomized Control Clinical Trial of FOLFOXIRI Preoperative Chemotherapy Alone on Rectal Cancer in Local Advance Comparing to Oral Capecitabine Combined With Long-term Radiation

Phase 3 Recruiting

Gastrointestinal

Rectal Neoplasms

NCT01037049 2018-09-17

Optimum Timing for Surgery After Pre-operative Radiotherapy 6 vs 12 Weeks

Phase 2 Unknown

Gastrointestinal

Adenocarcinoma, Carcinoma, Adenocarcinoma, Mucinous, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Rectal Diseases, Rectal Neoplasms, Colorectal Neoplasms, Neoplasms, Cystic, Mucinous, and Serous

NCT03177382 2018-05-08

TNTCRT

Phase 3 Unknown

Gastrointestinal

Rectal Neoplasms

NCT03085992 2018-03-14

TRUST

Phase 2 Completed

Gastrointestinal

Rectal Neoplasms

NCT01507103 2017-01-13

SPRINT

Phase 2 Completed

124 enrolled 9 charts

Gastrointestinal

Carcinoma, Neoplasms, Neoplasms by Site, Rectal Neoplasms

NCT00278694 2016-09-29

LARC-RRP

Phase 2 Completed

Gastrointestinal

Rectal Neoplasms

NCT02277158 2014-12-02

Phase I Study of CCRT as Adjuvant Treatment for Stage II/III Operable Rectal Cancer.

Phase 1 Unknown

Gastrointestinal

Rectal Neoplasms

NCT00738790 2010-04-15

Preoperative Radiotherapy and Local Excision in Rectal Cancer

Phase 3 Unknown

Gastrointestinal

Rectal Neoplasms

NCT00833131 2010-04-15

The Randomised Study of Preoperative Radiotherapy With Consolidating Chemotherapy for Unresectable Rectal Cancer

Phase 3 Unknown

Gastrointestinal

Rectal Neoplasms

NCT00808379 2008-12-15

Concurrent Chemo-Radiotherapy Versus Radiotherapy With Boost in Locally Advanced Unresectable Rectal Cancers

Phase 2 Unknown

Gastrointestinal

Rectal Neoplasms