Clinical Trials

Phase 3 Active not recruiting

Rectal Neoplasms

NCT04928807 2026-02-27

Short-Course Radiotherapy Followed by Neoadjuvant Chemotherapy and Camrelizumab in Locally Advanced Rectal Cancer (UNION)

231 enrolled

Rectal Neoplasms

NCT07397442 2026-02-11

Short-Course Radiotherapy Combined With Chemotherapy and Immunotherapy in Mid-Low Locally Advanced Rectal Cancer

19 enrolled

Pathologic Complete Response, Rectal Neoplasms

NCT04643366 2026-01-27

Total Neoadjuvant Therapy With mFOLFOX and Short-course Radiation in Resectable Rectal Cancer

54 enrolled

Rectal Neoplasms

NCT03875781 2026-01-15

NORAD01

Phase 3 Recruiting

540 enrolled

Rectal Neoplasms

NCT02314182 2025-12-19

GRECCAR8

Phase 3 Completed

5 enrolled

Rectal Neoplasms

NCT07161115 2025-09-15

REFIRT

60 enrolled

Rectal Neoplasms

NCT06958432 2025-08-07

Node-Sparing Short-Course Radiotherapy Sequential Chemotherapy and PD-1 Inhibitor for Mid/Low pMMR/MSS Rectal Cancer (MODIFI-RC-II)

Phase 2/3 Recruiting

430 enrolled

Rectal Neoplasms

NCT06501053 2025-06-06

CORRECT

Phase NA Recruiting

110 enrolled

Rectal Neoplasms

NCT06949098 2025-05-29

Tumor Local Excision +Postoperative Adjuvant Chemoradiotherapy for T1-2N0M0 Low/Ultra-Low Rectal Cancer

60 enrolled

Rectal Neoplasms

NCT06831981 2025-02-18

ARO 2024-13

Phase NA Recruiting

264 enrolled

Hyperthermia, Rectal Neoplasms

NCT06765616 2025-01-09

Adebrelimab Injection (PD-L1) Combined With Short Course Radiotherapy and Chemotherapy for Neoadjuvant Therapy of Locally Advanced Rectal Cancer

31 enrolled

Phase 3 Active not recruiting

Rectal Neoplasms

NCT02843191 2024-12-27

Consolidation Chemotherapy for Locally Advanced Mid or Low Rectal Cancer After Neoadjuvant Concurrent Chemoradiotherapy

358 enrolled

Rectal Neoplasms

NCT06665087 2024-10-30

CGA Guided Ultrafractionated RT and First-line Systemic Treatment in Elderly or Frail Patients with MCRC

110 enrolled

Colonic Neoplasms, Rectal Neoplasms

NCT06599827 2024-09-19

iMHRT-LARC

54 enrolled

Rectal Neoplasms

NCT06304545 2024-03-12

Treatment of Rectal Cancer With Long-term Concurrent Chemoradiotherapy Combined With Camrelizumab

48 enrolled

Rectal Neoplasms

NCT06254521 2024-02-12

The Effects of Neoadjuvant Tislelizumab Combined With Chemotherapy in Locally Advanced MSS Rectal Cancer

60 enrolled

Rectal Neoplasms

NCT01515787 2024-02-02

PROSPECT: Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing Surgery

Phase 2/3 Unknown

1,194 enrolled 25 charts

Rectal Neoplasms, Colorectal Neoplasms

NCT04558684 2024-01-03

Radiotherapy With Neoadjuvant Chemotherapy and Immunotherapy in Rectal Cancer

Phase 1/2 Suspended

30 enrolled

Rectal Neoplasms

NCT02528175 2023-12-07

Magnetic Resonance-Guided High Intensity Focused Ultrasound for Recurrent Rectal Cancer

6 enrolled

Rectal Neoplasms

NCT05939661 2023-07-11

AMBITION

45 enrolled

Rectal Neoplasms

NCT05868317 2023-05-22

Induction Chemotherapy Followed by Short Course Radiotherapy in Rectal Cancer

70 enrolled

Rectal Neoplasms

NCT05575635 2022-10-12

Neoadjuvant Treatment of Fruquintinib Combined With Concurrent Chemoradiotherapy for LARC

40 enrolled

Rectal Neoplasms

NCT03957733 2022-04-06

Phase II/III Study to Assess the Efficacy of Neoadjuvant Consolidation Chemotherapy in Rectal Cancer Patients.

Phase 2/3 Unknown

338 enrolled

Rectal Neoplasms

NCT00005944 2021-02-17

Second-look Surgery With or Without Intraperitoneal Chemotherapy in Treating Patients With Recurrent Colorectal Cancer

Phase 2 Terminated

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT01417494 2020-11-03

1st Line Chemotherapy Alone or With Bevacizumab in Treating Older Patients With Metastatic Colorectal Cancer

102 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT02178644 2020-10-08

Pilot Trial of KD018 With Neo-Adjuvant Concurrent Chemo-Radiation Therapy in Patients With Locally Advanced Rectal Cancer

Phase 1 Completed

29 enrolled

Rectal Neoplasms

NCT01471353 2020-07-23

SorCape

43 enrolled 12 charts

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms

NCT04288999 2020-06-04

JCOG1801

Phase 3 Recruiting

110 enrolled

Rectal Neoplasms

NCT03022734 2020-01-13

Short Course Radiotherapy, Unresectable Rectal Cancer, Liver Metastasis

40 enrolled

Neoplasm Metastasis, Rectal Neoplasms

NCT01923987 2019-09-20

Short Course Radiotherapy Followed Intensive Chemotherapy With Delayed Surgery for Rectal Cancer With Synchronous Distant Metastasis

39 enrolled

Rectal Neoplasms

NCT03634202 2019-05-15

DESIR

Phase NA Terminated

9 enrolled

Neoplasm Metastasis, Rectal Neoplasms

NCT00535041 2019-03-01

Pilot Trial of Pre-operative Chemo/RT Using Xeloda and External Beam RT Followed by Definite Surgery in Patients With Localized Rectal CA

200 enrolled

Rectal Neoplasms

NCT03561142 2018-06-19

CAO/ARO/AIO-16

94 enrolled

Rectal Neoplasms

NCT02353858 2018-02-13

HT01

78 enrolled

Hyperthermia, Pathologic Complete Response, Rectal Neoplasms

NCT00004891 2015-12-22

PET and CT Scans in Patients With Locally Advanced Primary Rectal Cancer That Can Be Removed During Surgery

149 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00537901 2015-12-17

First-Line Bevacizumab and Chemotherapy in Metastatic Cancer of the Colon or Rectum - International Study

100 enrolled

Colonic Neoplasms, Rectal Neoplasms

NCT00250835 2015-09-01

Combination of Oxaliplatin, Capecitabine, and Celecoxib With Concurrent Radiation for Rectal Cancer

Phase 2 Terminated

38 enrolled 11 charts

Neoplasms, Rectal Neoplasms

NCT00002896 2013-09-20

Radiation Therapy Plus Chemotherapy Before Surgery With or Without Chemotherapy After Surgery in Treating Patients With Rectal Cancer

Phase 3 Unknown

774 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00006112 2011-04-26

Fluorouracil With or Without Mitomycin in Treating Patients With Peritoneal Cancer

Appendiceal Neoplasms, Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00232453 2011-02-15

Preoperative Combined Radiation and Chemotherapy - Rectal Cancer

34 enrolled