Clinical Trials Browser

Bile Duct Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT05000697 2024-11-27

CCHOWW

Phase NA Recruiting

216 enrolled

Gastrointestinal

Pathologic Complete Response, Rectal Neoplasms

NCT05424692 2024-11-04

Drug Sensitivity Detection of Micro Tumor (PTC) to Guide Postoperative Adjuvant Treatment Strategy of Colorectal Cancer

Phase NA Recruiting

200 enrolled

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT06665087 2024-10-30

CGA Guided Ultrafractionated RT and First-line Systemic Treatment in Elderly or Frail Patients with MCRC

Phase 2 Not yet recruiting

110 enrolled

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT06652412 2024-10-28

CGA Guided Ultrafractionated RT and Systemic Treatment in Elderly or Frail Patients with Inoperable Localized CRC

Phase 2 Not yet recruiting

124 enrolled

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT00807911 2024-10-23

Adjuvant Chemotherapy After Preoperative Chemoradiotherapy to Treat Rectal Cancer

Phase 2 Completed

322 enrolled 20 charts

Gastrointestinal

Rectal Neoplasms

NCT05628038 2024-10-01

TORCH-R

Phase 2 Recruiting

93 enrolled

Gastrointestinal

Rectal Neoplasms

NCT04246684 2024-09-19

Short RT Versus RCT,Followed by Chemo.and Organ Preservation for Interm and High-risk Rectal Cancer Patients

Phase 3 Active not recruiting

702 enrolled

Gastrointestinal

Rectal Neoplasms

NCT03698461 2024-01-31

CLIMB

Phase 2 Completed

20 enrolled

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT02363374 2023-12-04

CAOAROAIO-12

Phase 2 Completed

311 enrolled

Gastrointestinal

Rectal Neoplasms

NCT02017704 2023-10-17

CORRECT

Phase 2 Completed

9 enrolled 9 charts

Gastrointestinal

Rectal Neoplasms

NCT05081687 2023-10-11

BRAZIL-TNT

Phase 3 Unknown

150 enrolled

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT01740648 2023-09-18

Trametinib, Fluorouracil, and Radiation Therapy Before Surgery in Treating Patients With Stage II-III Rectal Cancer

Phase 1 Completed

19 enrolled

Gastrointestinal

Rectal Neoplasms

NCT02232152 2023-08-07

CPI-613 and Fluorouracil in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed by Surgery

Phase 1 Completed

19 enrolled

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT05868317 2023-05-22

Induction Chemotherapy Followed by Short Course Radiotherapy in Rectal Cancer

Phase 2 Unknown

70 enrolled

Gastrointestinal

Rectal Neoplasms

NCT03299660 2023-03-16

Avelumab With Chemoradiation in Locally Advanced Rectal Cancer

Phase 2 Completed

37 enrolled

Gastrointestinal

Rectal Neoplasms

NCT03043729 2023-02-06

mFOLFOX6 vs. mFOLFOX6 + Aflibercept as Neoadjuvant Treatment in MRI-defined T3-rectal Cancer

Phase 2 Completed

119 enrolled

Gastrointestinal

Rectal Neoplasms

NCT00467142 2022-11-01

OMEGA

Phase 2 Completed

62 enrolled 6 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00936832 2022-08-30

Sunitinib Malate and Combination Chemotherapy as Front-Line Therapy in Treating Patients With Metastatic Rectal Cancer That Cannot Be Removed by Surgery

Phase 2 Withdrawn

Gastrointestinal

Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00280761 2022-08-11

Biomarkers in Patients With Rectal Cancer Undergoing Chemotherapy and Radiation Therapy

Completed

47 enrolled

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT01871571 2022-08-09

Bevacizumab, Fluorouracil, Leucovorin Calcium, and Oxaliplatin Before Surgery in Treating Patients With Stage II-III Rectal Cancer

Phase 2 Unknown

17 enrolled

Gastrointestinal

Rectal Neoplasms

NCT03000374 2022-03-17

PIER

Phase 2 Completed

34 enrolled

Gastrointestinal

Rectal Neoplasms

NCT05201430 2022-03-04

RCNAC

Phase 3 Recruiting

300 enrolled

Gastrointestinal

Rectal Neoplasms

NCT00308516 2021-12-10

5-Fluorouracil, Bevacizumab, and Radiation Followed by Modified FOLFOX6 and Bevacizumab in Stage II/III Rectal Cancer

Phase 2 Completed

66 enrolled 6 charts

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT04418895 2021-11-10

Neoadjuvant Therapy for Localized Rectal Adenocarcinoma

Phase 2 Withdrawn

Gastrointestinal

Rectal Neoplasms

NCT02319304 2021-11-04

GCC 1314

Phase 2 Terminated

3 enrolled 8 charts

Gastrointestinal

Rectal Neoplasms

NCT02270606 2021-07-20

Phase I Study of Neoadjuvant Radiotherapy With 5-Fluorouracil for Rectal Cancer

Phase 1 Completed

14 enrolled

Gastrointestinal

Rectal Neoplasms

Clinical Trials

Clinical Trial of Neoadjuvant mFOLFOX Plus Alvenor for LARC Patients With High YWHAB Expression

Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

ExIST Study of LY2157299 (Galunisertib) in Rectal Cancer

Short-course Radiotherapy or Long-course Chemoradiation Followed by mFOLFOXIRI Consolidation Chemotherapy for Organ Preservation in Low Rectal Cancer

Short Course Radiation Therapy and Combination Chemotherapy for the Treatment of Stage II-III Rectal Cancer

FRUITFUL

FOBEAR

Cetuximab and Combination Chemotherapy as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer

Preoperative FOLFOX Versus Postoperative Risk-adapted Chemotherapy in Patients With Locally Advanced Rectal Cancer

Radiation Therapy and Fluorouracil With or Without Combination Chemotherapy Followed by Surgery in Treating Patients With Stage II or Stage III Rectal Cancer

Preoperative ChemoRadiation And FOLFOXIRI for Rectal Cancer (CRAFTER) for Rectal Cancer

FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal Cancer

JANUS

COCHISE

Trial Evaluating 3-year Disease Free Survival in Patients With Locally Advanced Rectal Cancer Treated With Chemoradiation Plus Induction or Consolidation Chemotherapy and Total Mesorectal Excision or Non-operative Management

Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combined With Combination Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver

FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before Surgery

Ursodiol, Combination Chemotherapy, and Bevacizumab in Treating Patients With Stage IV Colorectal Cancer

Adjuvant Hepatic Arterial Infusion and Combination Chemotherapy in Treating Patients With Resectable Hepatic Metastases From Colorectal Cancer

ARO 2024-13

Aflibercept and FOLFOX6 Treatment for Previously Untreated Stage IV Colorectal Cancer

Panitumumab and Chemotherapy in Patients With Advanced Colorectal Cancer After Prior Therapy With Bevacizumab

Dasatinib for the Prevention of Oxaliplatin-Induced Neuropathy in Patients With Metastatic Gastrointestinal Cancer Receiving FOLFOX Chemotherapy With or Without Bevacizumab

CCHOWW

Drug Sensitivity Detection of Micro Tumor (PTC) to Guide Postoperative Adjuvant Treatment Strategy of Colorectal Cancer

CGA Guided Ultrafractionated RT and First-line Systemic Treatment in Elderly or Frail Patients with MCRC

CGA Guided Ultrafractionated RT and Systemic Treatment in Elderly or Frail Patients with Inoperable Localized CRC

Adjuvant Chemotherapy After Preoperative Chemoradiotherapy to Treat Rectal Cancer

TORCH-R

Short RT Versus RCT,Followed by Chemo.and Organ Preservation for Interm and High-risk Rectal Cancer Patients

CLIMB

CAOAROAIO-12

CORRECT

BRAZIL-TNT

Trametinib, Fluorouracil, and Radiation Therapy Before Surgery in Treating Patients With Stage II-III Rectal Cancer

CPI-613 and Fluorouracil in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed by Surgery

Induction Chemotherapy Followed by Short Course Radiotherapy in Rectal Cancer

Avelumab With Chemoradiation in Locally Advanced Rectal Cancer

mFOLFOX6 vs. mFOLFOX6 + Aflibercept as Neoadjuvant Treatment in MRI-defined T3-rectal Cancer

OMEGA

Sunitinib Malate and Combination Chemotherapy as Front-Line Therapy in Treating Patients With Metastatic Rectal Cancer That Cannot Be Removed by Surgery

Biomarkers in Patients With Rectal Cancer Undergoing Chemotherapy and Radiation Therapy

Bevacizumab, Fluorouracil, Leucovorin Calcium, and Oxaliplatin Before Surgery in Treating Patients With Stage II-III Rectal Cancer

PIER

RCNAC

5-Fluorouracil, Bevacizumab, and Radiation Followed by Modified FOLFOX6 and Bevacizumab in Stage II/III Rectal Cancer

Neoadjuvant Therapy for Localized Rectal Adenocarcinoma

GCC 1314

Phase I Study of Neoadjuvant Radiotherapy With 5-Fluorouracil for Rectal Cancer