Clinical Trials

Phase 2/3 Not yet recruiting

Rectal Neoplasms

NCT07134218 2025-08-21

Neoadjuvant Chemoradiotherapy Combined With Immunotherapy and Anti-angiogenesis in Treating Locally Advanced Rectal Cancer

180 enrolled

Rectal Neoplasms

NCT05496491 2024-10-08

Neoadjuvant Chemoradiotherapy and Consolidation Chemotherapy for Rectal Cancer: A Randomized Controlled Trial

Phase NA Recruiting

84 enrolled

Phase 3 Not yet recruiting

Neoplasms, Rectal Neoplasms

NCT06097416 2023-10-25

Neoadjuvant Chemoradiotherapy Versus Total Neoadjuvant Therapy in the Treatment of T3 Rectal Cancer

100 enrolled

Rectal Neoplasms

NCT01606098 2023-09-13

CAIRO4

Phase 3 Completed

206 enrolled

Colonic Neoplasms, Rectal Neoplasms

NCT05984485 2023-08-09

TaLaR-02

Phase 3 Recruiting

766 enrolled

Rectal Neoplasms

NCT01444495 2023-02-15

Randomized Clinical Trial on Preoperative Radiotherapy 25 Gy in Rectal Cancer

154 enrolled

Rectal Neoplasms

NCT05592873 2022-10-25

I-ONARC

317 enrolled

Rectal Neoplasms

NCT05496270 2022-08-11

Surgery Alone Versus Neoadjuvant Treatment Followed by Surgery For MRI-defined T3 Mid-low Rectal Cancer

1,509 enrolled

Rectal Neoplasms

NCT05495308 2022-08-10

"Oncologic Results and Risk Factors for Recurrence in Patients With Locally Advanced Rectal Cancer and Pathologic Complete Response After Neoadjuvant Treatment. Results From an Observational Retrospective Multicenter Long-term Follow-up Study".

4 enrolled

Rectal Neoplasms

NCT05339763 2022-04-21

Long Term Bowel Function Following Rectal Cancer Surgery

171 enrolled

Rectal Neoplasms, Irritable Bowel Syndrome

NCT00227747 2021-02-17

Radiation Therapy and Capecitabine With or Without Oxaliplatin in Treating Patients Who Are Undergoing Surgery for Stage II or Stage III Rectal Cancer

Phase 3 Completed

598 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00541112 2020-02-11

Radiation Therapy, Chemotherapy, and Cetuximab Followed by Surgery, Chemotherapy, and Cetuximab in Treating Patients With Locally Advanced or Metastatic Rectal Cancer That Can Be Removed by Surgery

Phase 2 Terminated

19 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT03899870 2019-04-02

Factors Predicting Recurrence in Rectal Cancer After Surgery

188 enrolled

Rectal Neoplasms, Recurrence

NCT00114231 2018-03-29

Capecitabine, Oxaliplatin, and Radiation Therapy in Treating Patients Who Are Undergoing Surgery for Stage I Rectal Cancer

Phase 2 Completed

90 enrolled 10 charts

Rectal Neoplasms, Colorectal Neoplasms

NCT00625183 2017-11-17

Capecitabine, Oxaliplatin, Selenomethionine, and Radiation Therapy in Treating Patients Undergoing Surgery For Newly Diagnosed Stage II or III Rectal Adenocarcinoma

Phase 2 Terminated

5 enrolled 6 charts

Rectal Neoplasms, Colorectal Neoplasms

NCT00972881 2017-10-25

EXCITE

Phase 1/2 Completed

82 enrolled

Rectal Neoplasms

NCT00408772 2017-06-09

Oxaliplatin, Capecitabine, and Bevacizumab Followed By Surgery and/or Radiofrequency Ablation in Patients With Colorectal Cancer

Phase 2 Withdrawn

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT03151759 2017-05-12

MMP-7

77 enrolled

Rectal Neoplasms

NCT03071198 2017-03-07

Clinical Effect of Neoadjuvant Hierarchical Treatment Based on Chemotherapy

Phase NA Unknown

1 enrolled

Rectal Neoplasms

NCT01263171 2016-09-21

COPERNICUS

Phase 2 Completed

60 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00216086 2016-06-06

Capecitabine + Irinotecan Followed by Combined Modality Capecitabine and Radiation in Locally Advanced Rectal Cancer

Phase 2 Terminated

22 enrolled 10 charts

Rectal Neoplasms

NCT00004891 2015-12-22

PET and CT Scans in Patients With Locally Advanced Primary Rectal Cancer That Can Be Removed During Surgery

149 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00084773 2015-12-22

Neoadjuvant Cetuximab, Fluorouracil, and Pelvic Irradiation in Treating Patients With Locally Advanced or Locally Recurrent Rectal Cancer

28 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00909987 2013-10-11

Study of Neoadjuvant CT With Selective Radiotherapy in Patients With Intermediate-Risk Cancer Rectum

Phase 2 Completed

46 enrolled

Rectal Neoplasms

NCT00005616 2013-06-19

Monoclonal Antibody Therapy in Treating Patients With Colorectal Cancer

Phase 1 Completed

12 enrolled

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00960427 2013-04-16

Studying Biomarkers in Tumor Tissue and Blood Samples From Patients Undergoing Chemotherapy and Radiation Therapy for Stage II or Stage III Rectal Cancer That Can Be Removed By Surgery

Phase 1 Withdrawn

Rectal Neoplasms, Colorectal Neoplasms

NCT00086931 2013-03-08

Oxaliplatin, Capecitabine, and Radiation Therapy in Treating Patients With Locally Advanced Cancer of the Rectum

Phase 1/2 Completed

37 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00608595 2013-03-05

Celecoxib in Treating Patients With Early-Stage Rectal Cancer

Phase NA Terminated

10 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00482222 2013-01-23

Combination Chemotherapy With or Without Cetuximab Before and After Surgery in Treating Patients With Resectable Liver Metastases Caused By Colorectal Cancer

Phase 3 Unknown

340 enrolled

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00084591 2010-02-12

Intensity-Modulated Radiation Therapy With Incorporated Boost and Capecitabine Before Surgery in Treating Patients With Locally Advanced Rectal Cancer

Phase 1 Completed

Rectal Neoplasms, Colorectal Neoplasms

NCT00383695 2010-01-13

EXPERT-C

Phase 2 Unknown

164 enrolled