Clinical Trials Browser

Rectal Neoplasms

NCT05358704 2025-12-04

Preoperative ChemoRadiation And FOLFOXIRI for Rectal Cancer (CRAFTER) for Rectal Cancer

Phase 2 Suspended

38 enrolled

Gastrointestinal

Rectal Neoplasms

NCT06780787 2025-06-26

FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before Surgery

Phase 2 Recruiting

26 enrolled

Gastrointestinal

Rectal Neoplasms

NCT06751394 2024-12-27

TRACER

Phase 2 Not yet recruiting

44 enrolled

Gastrointestinal

Rectal Neoplasms

NCT05628038 2024-10-01

TORCH-R

Phase 2 Recruiting

93 enrolled

Gastrointestinal

Rectal Neoplasms

NCT06455124 2024-06-13

Short-course Radiotherapy Combined With CapeOx and PD-1 Inhibitor After Local Excision for High-risk Early Rectal Cancer (TORCH-LE)

Phase 2 Recruiting

60 enrolled

Gastrointestinal

Rectal Neoplasms

NCT05228431 2024-04-22

Modified Sandwich Therapeutic Regimen for Locally Advanced Rectal Cancer

Phase 2 Recruiting

121 enrolled

Gastrointestinal

Rectal Neoplasms

NCT00745134 2023-09-28

Radiation Therapy and Capecitabine With or Without Curcumin Before Surgery in Treating Patients With Rectal Cancer

Phase 2 Terminated

22 enrolled 16 charts

Gastrointestinal

Rectal Neoplasms

NCT05939661 2023-07-11

AMBITION

Phase 2 Recruiting

45 enrolled

Gastrointestinal

Rectal Neoplasms

NCT02641691 2021-02-18

NORMAL-R

Phase 2 Completed

20 enrolled 11 charts

Gastrointestinal

Rectal Neoplasms

NCT00353457 2020-04-09

Capecitabine,Oxaliplatin & Erbitux Given Throughout Multi-Modal Therapy for Locally Advanced Rectal Adenocarcinoma

Phase 2 Terminated

6 enrolled

Gastrointestinal

Rectal Neoplasms

NCT00321685 2019-03-27

Bevacizumab, Radiation Therapy, and Combination Chemotherapy in Treating Patients Who Are Undergoing Surgery for Locally Advanced Nonmetastatic Rectal Cancer

Phase 2 Completed

57 enrolled 10 charts

Gastrointestinal

Rectal Neoplasms

NCT00611858 2019-01-08

Cetuximab, 5-FU and Radiation as Neoadjuvant Therapy for Patients With Locally Advanced Rectal Cancer

Phase 2 Terminated

13 enrolled 9 charts

Gastrointestinal

Rectal Neoplasms

NCT00114231 2018-03-29

Capecitabine, Oxaliplatin, and Radiation Therapy in Treating Patients Who Are Undergoing Surgery for Stage I Rectal Cancer

Phase 2 Completed

90 enrolled 10 charts

Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT01729923 2018-01-16

ADAPT

Phase 2 Terminated

27 enrolled 10 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT00682786 2017-10-06

Genotype-directed Neoadjuvant Chemoradiation for Rectal Carcinoma

Phase 2 Completed

135 enrolled 17 charts

Gastrointestinal

Carcinoma, Neoplasms, Rectal Neoplasms

NCT01749956 2017-02-07

5-FU, Aflibercept, and Radiation (RT) for Preoperative and Postoperative Patients With Stage II/III Rectal Cancer

Phase 2 Completed

39 enrolled 13 charts

Gastrointestinal

Rectal Neoplasms

NCT00250835 2015-09-01

Combination of Oxaliplatin, Capecitabine, and Celecoxib With Concurrent Radiation for Rectal Cancer

Phase 2 Terminated

38 enrolled 11 charts

Gastrointestinal

Neoplasms, Rectal Neoplasms

NCT01818973 2015-06-08

Preoporative Bevacizumab, Radiation Therapy, and XELOX Chemotherapy for Locally Advanced Nonmetastatic Rectal Cancer

Phase 2 Unknown

45 enrolled

Gastrointestinal

Rectal Neoplasms

NCT00842686 2012-03-26

CRAB

Phase 2 Unknown

60 enrolled

Gastrointestinal

Rectal Neoplasms

NCT00176787 2008-01-10

Radiation Therapy With Capecitabine in Rectal Cancer

Phase 2 Terminated

30 enrolled

Gastrointestinal

Rectal Neoplasms

NCT00346099 2008-01-07

Study of Panitumumab Given First With Capecitabine and Oxaliplatin (CAPOX) and Then With Capecitabine and Radiation of the Pelvis for Treatment of Patients With Rectal Cancers That May or May Not Have Spread Beyond the Rectum

Phase 2 Withdrawn

Gastrointestinal

Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

Clinical Trials

Testing Nivolumab and Ipilimumab With Short-Course Radiation in Locally Advanced Rectal Cancer

Preoperative ChemoRadiation And FOLFOXIRI for Rectal Cancer (CRAFTER) for Rectal Cancer

FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before Surgery

TRACER

TORCH-R

Short-course Radiotherapy Combined With CapeOx and PD-1 Inhibitor After Local Excision for High-risk Early Rectal Cancer (TORCH-LE)

Modified Sandwich Therapeutic Regimen for Locally Advanced Rectal Cancer

Radiation Therapy and Capecitabine With or Without Curcumin Before Surgery in Treating Patients With Rectal Cancer

AMBITION

NORMAL-R

Capecitabine,Oxaliplatin & Erbitux Given Throughout Multi-Modal Therapy for Locally Advanced Rectal Adenocarcinoma

Bevacizumab, Radiation Therapy, and Combination Chemotherapy in Treating Patients Who Are Undergoing Surgery for Locally Advanced Nonmetastatic Rectal Cancer

Cetuximab, 5-FU and Radiation as Neoadjuvant Therapy for Patients With Locally Advanced Rectal Cancer

Capecitabine, Oxaliplatin, and Radiation Therapy in Treating Patients Who Are Undergoing Surgery for Stage I Rectal Cancer

ADAPT

Genotype-directed Neoadjuvant Chemoradiation for Rectal Carcinoma

5-FU, Aflibercept, and Radiation (RT) for Preoperative and Postoperative Patients With Stage II/III Rectal Cancer

Combination of Oxaliplatin, Capecitabine, and Celecoxib With Concurrent Radiation for Rectal Cancer

Preoporative Bevacizumab, Radiation Therapy, and XELOX Chemotherapy for Locally Advanced Nonmetastatic Rectal Cancer

CRAB

Radiation Therapy With Capecitabine in Rectal Cancer

Study of Panitumumab Given First With Capecitabine and Oxaliplatin (CAPOX) and Then With Capecitabine and Radiation of the Pelvis for Treatment of Patients With Rectal Cancers That May or May Not Have Spread Beyond the Rectum