Clinical Trials Browser

Interventional × Rectal Neoplasms × XELOX × Clear all

NCT04495088 2026-02-02

Preoperative FOLFOX Versus Postoperative Risk-adapted Chemotherapy in Patients With Locally Advanced Rectal Cancer

Phase 3 Recruiting

Gastrointestinal

Rectal Neoplasms

NCT07127497 2025-11-21

Clinical Study on the Safety and Relationship of Sintilimab Combined With Chemotherapy in Neoadjuvant Treatment of Locally Advanced Rectal Adenocarcinoma

Phase 2 Active not recruiting

Gastrointestinal

Rectal Neoplasms

NCT07132463 2025-08-20

Neoadjuvant Chemoradiotherapy Followed by Chemotherapy With or Without Tislelizumab for Resectable Ultra-low Rectal Cancer: The RELIEVE-02 Study

Phase 3 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT07108127 2025-08-06

NePHera

Phase 2 Recruiting

Gastrointestinal

Rectal Neoplasms

NCT01643070 2025-02-25

Preoperative CRT With or Without Induction Chemotherapy for Rectal Cancer With Liver Metastases

Phase 2 Completed

38 enrolled 16 charts

Gastrointestinal

Rectal Neoplasms

NCT04380337 2025-02-25

Organ Preservation Program Using Short-Course Radiation & FOLFOXIRI in Rectal Cancer

Phase 2 Completed

38 enrolled 13 charts

Gastrointestinal

Rectal Neoplasms

NCT03565029 2024-12-27

NO-CUT

Phase 2 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT03714490 2024-05-29

SUNRISE

Phase 2 Recruiting

Gastrointestinal

Rectal Neoplasms

NCT05228431 2024-04-22

Modified Sandwich Therapeutic Regimen for Locally Advanced Rectal Cancer

Phase 2 Recruiting

Gastrointestinal

Rectal Neoplasms

NCT04543695 2024-03-26

A Study of Total Neoadjuvant Therapy for High-risk Locally Advanced Rectal Cancer

Phase 2 Unknown

Gastrointestinal

Rectal Neoplasms

NCT03840239 2023-10-25

TESS

Phase 2 Active not recruiting

Gastrointestinal

Rectal Neoplasms

NCT05969847 2023-08-01

TRACE-LE

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT05420584 2023-05-11

NECI

Phase 2 Unknown

Gastrointestinal

Rectal Neoplasms

NCT03666442 2022-04-29

Early Evaluation of Chemosensitivity for Low/Intermediated-risk Mid-low Stage II/III Rectal Cancer

Phase 2 Completed

Gastrointestinal

Rectal Neoplasms

NCT03957733 2022-04-06

Phase II/III Study to Assess the Efficacy of Neoadjuvant Consolidation Chemotherapy in Rectal Cancer Patients.

Phase 2/3 Unknown

Gastrointestinal

Rectal Neoplasms

NCT04418895 2021-11-10

Neoadjuvant Therapy for Localized Rectal Adenocarcinoma

Phase 2 Withdrawn

Gastrointestinal

Rectal Neoplasms

NCT03484221 2021-04-14

Totally Neoadjuvant FOLFOXIRI + Short-course Radiation + XELOX in Patients With Locally Advanced Rectal Cancer

Phase 2 Unknown

Gastrointestinal

Rectal Neoplasms

NCT04747951 2021-02-15

Total Neoadjuvant Therapy in Rectal Cancer Treatment

Phase 4 Unknown

Gastrointestinal

Rectal Neoplasms

NCT03671252 2019-01-23

Prospectively Randomized Control Clinical Trial of FOLFOXIRI Preoperative Chemotherapy Alone on Rectal Cancer in Local Advance Comparing to Oral Capecitabine Combined With Long-term Radiation

Phase 3 Recruiting

Gastrointestinal

Rectal Neoplasms

NCT03415763 2018-11-06

Adjuvant Chemotherapy in Patients With Clinical Stage III Rectal Cancer Undergoing Neoadjuvant Chemoradiotherapy

Phase 3 Unknown

Gastrointestinal

Rectal Neoplasms

NCT01952951 2017-09-13

PREPARE

Phase 2 Unknown

Gastrointestinal

Adenocarcinoma, Rectal Neoplasms

NCT00127036 2017-03-23

Trial for Microarray Analysis of Colon Cancer Outcome-A (MACCO-A)

Phase 2 Terminated

65 enrolled 8 charts

Gastrointestinal

Adenocarcinoma, Colonic Neoplasms, Rectal Neoplasms

NCT03038217 2017-02-03

Investigation of the Value of ctDNA in Diagnosis, Treatment, and Surveillance of Surgically Resectable Colorectal Cancer

Phase 3 Unknown

Gastrointestinal

Rectal Neoplasms

NCT02745639 2016-04-20

GRACE

Phase 2 Completed

Gastrointestinal

Rectal Neoplasms

NCT02022852 2013-12-30

Neoadjuvant Sequential Therapy in Locally Advanced Mid/Low Rectal Cancer

Phase 2 Unknown

Gastrointestinal

Rectal Neoplasms