Clinical Trials

45 enrolled

Phase 1/2 Not yet recruiting

Rectal Neoplasms

NCT06783153 2025-01-20

Efficacy and Safety of Adjunctive Use of Rifaximin In Preventing Radiotherapy-induced Diarrhea in Cancer Patients

80 enrolled

GastrointestinalGenitourinary

Neoplasms, Prostatic Neoplasms, Rectal Neoplasms

NCT02861300 2024-12-19

CB-839 + Capecitabine in Solid Tumors and Fluoropyrimidine Resistant PIK3CA Mutant Colorectal Cancer

50 enrolled 16 charts

Colonic Neoplasms, Hereditary Sensory and Autonomic Neuropathies, Rectal Neoplasms, Colorectal Neoplasms

NCT03436563 2024-11-27

M7824 in Patients With Metastatic Colorectal Cancer or With Advanced Solid Tumors With Microsatellite Instability

4 enrolled 7 charts

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms, Microsatellite Instability

NCT06530303 2024-11-05

BAH248

Phase 1/2 Recruiting

85 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT04636008 2024-08-06

Sintilimab Plus Hypofractionated Radiotherapy for MSI-H/dMMR Rectal Cancer

Phase 1/2 Recruiting

Turcot syndrome, Rectal Neoplasms

NCT06395337 2024-05-02

MIRCA & MIPAC

Pancreatic Neoplasms, Rectal Neoplasms

NCT05111860 2024-03-07

Neoadjuvant Bevacizumab + Chemotherapy Combined With Short-course Radiotherapy

Rectal Neoplasms

NCT04558684 2024-01-03

Radiotherapy With Neoadjuvant Chemotherapy and Immunotherapy in Rectal Cancer

Phase 1/2 Suspended

30 enrolled

Rectal Neoplasms

NCT05911789 2023-08-01

Online Adaptive Radiation Therapy for Rectal Cancer

15 enrolled

Rectal Neoplasms

NCT04177602 2023-02-22

Evaluating Trifluridine/Tipiracil Based Chemoradiation in Locally Advanced Rectal Cancer - The Phase I/II TARC Trial

10 enrolled

Rectal Neoplasms

NCT02948348 2021-09-16

Study to Nivolumab Following Preoperative Chemoradiotherapy

90 enrolled

Rectal Neoplasms

NCT02393755 2021-07-08

Nintedanib and Capecitabine in Treating Patients With Refractory Metastatic Colorectal Cancer

42 enrolled 16 charts

Colonic Neoplasms, Rectal Neoplasms

NCT04231552 2020-11-30

Preoperative Short Course Radiotherapy With Chemotherapy and Camerelizumab in Locally Advanced Rectal Cancer

30 enrolled

Rectal Neoplasms

NCT01097239 2020-11-20

Examining the Role of Transrectal High Intensity Focused Ultrasound (HIFU) in Rectal Pelvic Cancer

GastrointestinalGynecologic

Uterine Cervical Neoplasms, Ovarian Neoplasms, Rectal Neoplasms, Vaginal Neoplasms, Endometrial Neoplasms

NCT02010567 2020-11-03

Neoadjuvant Chemoradiotherapy With CRLX-101 and Capecitabine for Rectal Cancer

32 enrolled 18 charts

Rectal Neoplasms, Colorectal Neoplasms

NCT01302613 2020-08-20

Altered Chemotherapy Sequencing During Neoadjuvant Therapy for Patients With Stage II or III Rectal Adenocarcinoma

Rectal Neoplasms

NCT00003225 2020-08-03

Amifostine Plus Irinotecan in Treating Patients With Metastatic Colorectal Cancer

23 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT01806675 2019-10-03

18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy

BreastCNSGastrointestinalGenitourinaryHead & NeckSarcomaThoracic

25 enrolled 14 charts

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Glioblastoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Salivary Gland Neoplasms, Tongue Neoplasms, Esthesioneuroblastoma, Olfactory, Gliosarcoma, Breast Neoplasms, Male

NCT03204201 2019-08-13

Validation of ICG to Identify the Urethra During Rectal Surgery

5 enrolled

Rectal Neoplasms

NCT03204994 2019-08-13

Fluorescence Targeted Pelvic Lymph Node Mapping

1 enrolled

Rectal Neoplasms

NCT00004187 2019-06-26

Capecitabine and Oxaliplatin in Treating Patients With Advanced or Metastatic Colorectal Cancer

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00869570 2019-05-15

External-Beam Radiation Therapy, Capecitabine, and Sorafenib in Treating Patients With Locally Advanced Rectal Cancer

54 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT01985763 2019-05-10

Genistein in Treatment of Metastatic Colorectal Cancer

13 enrolled 17 charts

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT01206530 2019-04-18

FOLFOX/Bevacizumab/Hydroxychloroquine (HCQ) in Colorectal Cancer

50 enrolled

Adenocarcinoma, Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms

NCT00645710 2019-03-28

Hepatic Arterial Infusion of Floxuridine, Gemcitabine Hydrochloride, and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer Previously Treated With Surgery

16 enrolled 12 charts

Colonic Neoplasms, Rectal Neoplasms

NCT00409994 2019-03-18

Safety Study of Rapamycin Administered Before and During Radiotherapy to Treat Rectum Cancer

44 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00003344 2018-05-16

Radiation Therapy Plus Irinotecan in Treating Patients With Colon Cancer

49 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00226941 2017-12-08

A Phase 1-2 Trial of Cetuximab in Combination With Oxaliplatin, Capecitabine, and Radiation Therapy Followed by Surgery for Locally-advanced Rectal Cancer

23 enrolled 18 charts

Colonic Neoplasms, Rectal Neoplasms

NCT00972881 2017-10-25

EXCITE

82 enrolled

Rectal Neoplasms

NCT01716949 2017-08-11

HyRec

59 enrolled

Hyperthermia, Rectal Neoplasms

NCT00307736 2017-05-10

Bevacizumab, Erlotinib and 5-Fluorouracil With External Beam Radiation Therapy in Locally Advanced Rectal Cancer

32 enrolled 14 charts

Rectal Neoplasms

NCT01150877 2017-03-03

High Dose Vitamin D Study

40 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT02236884 2016-12-19

The Feasibility and Safety of No-scar Transanal Total Mesorectal Excision for Rectal Cancer

Rectal Neoplasms

NCT02575508 2016-05-20

Pan FGFR Kinase Inhibitor BGJ398 and Combination Chemotherapy in Treating Patients With Untreated Metastatic Pancreatic Cancer

Colonic Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms

NCT00575640 2015-03-04

Hydralazine as a Demethylating Agent in Rectal Cancer

Rectal Neoplasms

NCT00026299 2013-09-05

Oxaliplatin With or Without Gefitinib in Treating Patients With Metastatic or Locally Recurrent Colorectal Cancer

14 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00003103 2013-07-03

Chemotherapy in Treating Patients With Solid Tumors