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Phase

Phase 2 2Phase NA 1Phase 2/3 1Phase 1/2 1Phase 1 1

Status

Completed 130Terminated 32Unknown 12Recruiting 12Active not recruiting 8Withdrawn 6Suspended 1Not yet recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Plasma cell 1Other hematologic neoplasm 1Myeloid 1Lymphoid 1Gastrointestinal 1

Conditions

Leukemia, Myeloid, Acute 13Neoplasms 12Neoplasm Metastasis 9Melanoma 7Prostatic Neoplasms 6Ovarian Neoplasms 6Myelodysplastic Syndromes 6Breast Neoplasms 6Pancreatic Neoplasms 5Lung Neoplasms 5Glioma 5Colorectal Neoplasms 5Precursor Cell Lymphoblastic Leukemia-Lymphoma 4Hematologic Neoplasms 4Glioblastoma 4Triple Negative Breast Neoplasms 3Stomach Neoplasms 3Small Cell Lung Carcinoma 3Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Lymphoma 3Head and Neck Neoplasms 3Carcinoma, Renal Cell 3Carcinoma, Non-Small-Cell Lung 3Unspecified Adult Solid Tumor, Protocol Specific 2Solid Tumors 2Solid Tumor 2Sarcoma 2Osteosarcoma 2Lymphoma, T-Cell, Peripheral 2Lymphoma, B-Cell 2

Interventions

vactosertib 1fludarabine phosphate 1aldesleukin 1Interleukin-2 1IL32 protein, human 1Cyclophosphamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1 × Suspended × Rectal Neoplasms × Clear all
NCT05400122 2025-11-12

Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer

Case Comprehensive Cancer Center

Phase 1 Suspended
12 enrolled
GastrointestinalLymphoidMyeloidOther hematologic neoplasmPlasma cell

Esophageal Neoplasms, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Neoplasm Metastasis, Rectal Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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