Clinical Trials Browser

Phase 2 × Not yet recruiting × Rectal Neoplasms × Clear all

NCT07527520 2026-04-14

Neoadjuvant Moderately Hypofractionated Radiotherapy Combined With Chemotherapy and Immunotherapy for High-risk pMMR/MSS Locally Advanced Rectal Cancer: A Prospective, Multi-center Randomized Control Phase II Trial

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT07516210 2026-04-07

ART-Hypo

Phase 2 Not yet recruiting

GastrointestinalGenitourinaryGynecologic

Uterine Cervical Neoplasms, Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Endometrial Neoplasms

NCT07509424 2026-04-03

Neoadjuvant Short-course Radiotherapy Followed by a Combination of Disitamab Vedotin, Sintilimab, and Capecitabine in Locally Advanced HER2-expressing Rectal Cance

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT07281768 2026-03-20

Capecitabine/Oxaliplatin Chemotherapy and Cemiplimab With or Without Fianlimab or REGN7075 in Locally Advanced Rectal Cancer

Phase 2 Not yet recruiting

Gastrointestinal

Adenocarcinoma, Carcinoma, Rectal Neoplasms, Colorectal Neoplasms

NCT07176182 2026-02-27

Clinical Trial of Neoadjuvant mFOLFOX Plus Alvenor for LARC Patients With High YWHAB Expression

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT07397442 2026-02-11

Short-Course Radiotherapy Combined With Chemotherapy and Immunotherapy in Mid-Low Locally Advanced Rectal Cancer

Phase 2 Not yet recruiting

Gastrointestinal

Pathologic Complete Response, Rectal Neoplasms

NCT07402486 2026-02-11

A Phase II Prospective Study of Maastro Applicator Brachytherapy for Rectal Cancer

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT07394192 2026-02-06

PKUCH- R11

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT07381400 2026-02-03

Neoadjuvant mFOLFOX6 Chemotherapy Combined With Anti-PD-1 Therapy in MSS/pMMR Locally Advanced Rectal Cancer (FIRM02 Study)

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT07209215 2026-01-20

ULTIMATE

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT07302126 2025-12-24

Preventive Efficacy of Bergmann Enema for Acute Radiation-induced Rectal Injury in Rectal Cancer Patients Undergoing Short-course Radiotherapy

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT07297030 2025-12-22

SIB-RT Combined With CAPOX and PD-1 for High-Risk Rectal Cancer

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT07248020 2025-11-25

BCMRECRAD

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT07239466 2025-11-20

A Pilot Study Evaluating β-hydroxybutyrate Supplementation Concomitant to Short-Course Radiotherapy Followed by Immunotherapy Combined With CAPEOX Neoadjuvant Therapy in Patients With Locally Advanced Rectal Cancer

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT07175636 2025-09-16

QL1706 With Short-Course Radiotherapy and Chemotherapy for MSS Rectal Cancer

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT07161115 2025-09-15

REFIRT

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT07162714 2025-09-09

STAR

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT06057831 2025-06-18

PET/MRI in Rectal Cancer

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT06919510 2025-04-09

A Phase ll Study of Neoadjuvant Short-course Radiotherapy Followed by Ivonescimab and Chemotherapy in pMMR/MSS Locally Advanced Rectal Cancer

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT06872606 2025-03-12

SCRIPBOT

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT06751394 2024-12-27

TRACER

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT06665087 2024-10-30

CGA Guided Ultrafractionated RT and First-line Systemic Treatment in Elderly or Frail Patients with MCRC

Phase 2 Not yet recruiting

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT06652412 2024-10-28

CGA Guided Ultrafractionated RT and Systemic Treatment in Elderly or Frail Patients with Inoperable Localized CRC

Phase 2 Not yet recruiting

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT06599827 2024-09-19

iMHRT-LARC

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT06390982 2024-04-30

Organ Preservation With Tislelizumab and Total Neoadjuvant Therapy in Patients With Low Rectal Cancer: RELIEVE -01 Study

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT06255379 2024-04-29

Study of Fruquintinib Combined With Tegafur Gimeracil Oteracil in Patients With Metastatic Colorectal Cancer

Phase 2 Not yet recruiting

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT06304545 2024-03-12

Treatment of Rectal Cancer With Long-term Concurrent Chemoradiotherapy Combined With Camrelizumab

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT04889742 2023-12-26

HETERERO

Phase 2 Not yet recruiting

EndocrineGastrointestinalGenitourinaryGynecologicNETSarcoma

Hyperthermia, Anus Neoplasms, Carcinoma, Squamous Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Fever, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Recurrence, Sarcoma, Neuroendocrine Tumors

NCT06014944 2023-08-31

PMMR/MSS

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT05969847 2023-08-01

TRACE-LE

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT05807984 2023-04-11

Re-irradiation Therapy of Locally Recurrent Rectal Cancer With Carbon Ion

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms, Recurrence

NCT05640726 2022-12-07

The First-line Treatment of RCLM With RAS Mutation Was Local Short-course Radiotherapy (SCRT) + PD-1+ Standard Therapy

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT05507112 2022-09-21

TIMENT-R

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT04838496 2021-04-09

MEND-IT

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms

NCT04443543 2020-06-30

An Adaptive-design Prospective Cohort Study of Watch and Wait Strategy in Patients With Locally Advanced Rectal Cancer

Phase 2 Not yet recruiting

Gastrointestinal

Rectal Neoplasms