Clinical Trials

Phase EARLY_PHASE1 Recruiting

100 enrolled

BreastGastrointestinal

Intermittent Fasting, Breast Neoplasms, Rectal Neoplasms

NCT03594630 2026-05-20

Active Surveillance and Chemotherapy Before Surgery in Treating Participants With Stage II-III Rectal Cancer

120 enrolled

Rectal Neoplasms

NCT07594925 2026-05-19

Short-Course Radiotherapy Followed by Immunotherapy Combined With Chemotherapy for Microsatellite Stable Locally Advanced Rectal Cancer: A Prospective, Randomized, Controlled Phase II Clinical Trial

130 enrolled

Rectal Neoplasms

NCT07596732 2026-05-19

SUNRISE

Phase NA Active not recruiting

120 enrolled

GastrointestinalThoracic

Colonic Neoplasms, Disease, Esophageal Neoplasms, Lung Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT05056077 2026-05-18

TTBF

353 enrolled

BreastGastrointestinalGenitourinaryGynecologic

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Renal Cell, Colonic Neoplasms, Kidney Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Endometrial Neoplasms

NCT01408407 2026-05-14

Alkagin Paste in the Prevention of Radiation Dermatitis

Phase 2 Terminated

2 enrolled

Anus Neoplasms, Rectal Neoplasms, Urogenital Neoplasms

NCT02514278 2026-05-14

GRECCAR12

Phase 3 Completed

218 enrolled

Rectal Neoplasms

NCT05715255 2026-05-14

Adaptive Symptom Self-Management Immunotherapy Study

BreastDermatologicGastrointestinalThoracic

400 enrolled

Breast Neoplasms, Colonic Neoplasms, Lung Neoplasms, Neoplasms, Rectal Neoplasms, Skin Neoplasms

NCT04165772 2026-05-13

Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors

212 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckThoracic

Rectal Neoplasms

NCT06673329 2026-05-13

Brodalumab in the Treatment of Immune-Related Adverse Events

Phase 1 Recruiting

11 enrolled

Brain Neoplasms, Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Mouth Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Thyroid Neoplasms

NCT07113275 2026-05-13

A Clinical Trial Comparing Long-Course Versus Short-Course Radiotherapy Followed by Immunotherapy Combined With Total Neoadjuvant Therapy (TNT) to Long-Course Radiotherapy Followed by TNT in Locally Advanced Rectal Cancer

444 enrolled

Rectal Neoplasms

NCT07463261 2026-05-13

RELOAD

442 enrolled

Rectal Neoplasms, Anastomotic Leak

NCT05672524 2026-05-12

A Study of Tucatinib and Trastuzumab in People With Rectal Cancer

37 enrolled

Adenocarcinoma, Rectal Neoplasms

NCT05682157 2026-05-12

Paula Method of Exercises in Patients With LARS Syndrome:Randomized Controlled Trial

Phase NA Completed

62 enrolled

Low Anterior Resection Syndrome, Encopresis, Rectal Neoplasms

NCT06123156 2026-05-12

RECTIL

188 enrolled

GastrointestinalGynecologicThoracic

Rectal Neoplasms

NCT07458347 2026-05-12

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

Phase 1 Recruiting

145 enrolled

Biliary Tract Neoplasms, Colonic Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT07580339 2026-05-12

Combining DCSZ11 With Radiation and Chemotherapy as Neoadjuvant Treatment for pMMR Locally Advanced Rectal Cancer

Phase 2 Not yet recruiting

30 enrolled

Rectal Neoplasms

NCT06758830 2026-05-11

Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer.

Phase 2/3 Recruiting

400 enrolled

Phase NA Enrolling by invitation

Low Anterior Resection Syndrome, Fatigue, Postoperative Complications, Radiation Injuries, Rectal Neoplasms

NCT07253298 2026-05-11

BFT in LARS

66 enrolled

Low Anterior Resection Syndrome, Intestinal Diseases, Rectal Neoplasms

NCT07283939 2026-05-11

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

420 enrolled

Appendiceal Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT06149741 2026-05-08

STOMALEFT

Phase NA Terminated

16 enrolled

Rectal Neoplasms

NCT06204497 2026-05-08

The Safety and Efficiency of Stent-based Diverting Technique Versus Ileostomy in Rectal Cancer Patients

Phase NA Completed

570 enrolled

Rectal Neoplasms, Anastomotic Leak

NCT05080673 2026-05-07

FORTE

9,500 enrolled

Colonic Neoplasms, Rectal Neoplasms

NCT06936774 2026-05-06

iRECOVER

140 enrolled

Phase 2 Not yet recruiting

Low Anterior Resection Syndrome, Rectal Neoplasms

NCT07281768 2026-05-06

Capecitabine/Oxaliplatin Chemotherapy and Cemiplimab With or Without Fianlimab or REGN7075 in Locally Advanced Rectal Cancer

66 enrolled

Adenocarcinoma, Carcinoma, Rectal Neoplasms, Colorectal Neoplasms

NCT07552207 2026-05-04

PKUCH-R12

30 enrolled

Lymphatic Metastasis, Rectal Neoplasms

NCT07563907 2026-05-04

OPTION

292 enrolled

Phase 3 Active not recruiting

Rectal Neoplasms

NCT01558921 2026-05-01

RAPIDO

920 enrolled 17 charts

Rectal Neoplasms

NCT06729645 2026-05-01

ACO/ARO/AIO-22

80 enrolled

Rectal Neoplasms

NCT07561060 2026-05-01

TNTIT

Phase 1/2 Recruiting

50 enrolled

Rectal Neoplasms

NCT05297734 2026-04-30

Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicMyeloidSarcomaThoracic

2,996 enrolled

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Death, Esophageal Neoplasms, Glioblastoma, Lung Diseases, Lung Neoplasms, Melanoma, Myelodysplastic Syndromes, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Sarcoma, Osteosarcoma, Skin Neoplasms, Stomach Neoplasms, Thoracic Neoplasms, Urogenital Neoplasms, Disease Progression, Small Cell Lung Carcinoma

NCT07499921 2026-04-30

BIOREC

300 enrolled

Rectal Neoplasms

NCT07528209 2026-04-30

Neoadjuvant CAPOX With or Without Pucotenlimab Plus Selective Radiotherapy for Locally Advanced Rectal Cancer

556 enrolled

Phase NA Active not recruiting

Rectal Neoplasms

NCT04084249 2026-04-29

ctDNA-guided Surveillance for Stage III CRC, a Randomized Intervention Trial

359 enrolled

Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Neoplasms, Rectal Diseases, Rectal Neoplasms, Colorectal Neoplasms

NCT06850090 2026-04-28

Neoadjuvant Radiotherapy for Rectal Adenocarcinoma With Capecitabine Versus TAS-102 (Neo-REACT): A Multi-center, Randomized, Phase III Trial

210 enrolled

Rectal Neoplasms

NCT06911684 2026-04-28

Radiotherapy Plus Iparomlimab and Tuvonralimab (QL1706), Regorafenib, and CAPOX as Neoadjuvant Therapy for pMMR/MSS LARC.

88 enrolled

Rectal Neoplasms

NCT04643041 2026-04-27

BASKET

47 enrolled

Rectal Neoplasms

NCT04677413 2026-04-27

Ultra-fractionated Radiotherapy for Rectal Cancer

Phase 1 Recruiting

27 enrolled

Rectal Neoplasms

NCT04336202 2026-04-24

Whistle

Phase NA Suspended

45 enrolled

Rectal Neoplasms

NCT06204094 2026-04-24

CASINOs

37 enrolled

Phase 3 Not yet recruiting

Rectal Neoplasms

NCT07549399 2026-04-24

CRITⅡ

204 enrolled